Intermediates

1-(4-Nitrophenyl)piperidin-2-one

  • CAS No.38560-30-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 1-(4-Nitrophenyl)piperidin-2-one designed for pharmaceutical synthesis. Reliable supply for Apixaban intermediate production with full documentation.

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Product Technical Details

Product Overview

1-(4-Nitrophenyl)piperidin-2-one is a specialized organic compound widely recognized for its critical role in the synthesis of advanced pharmaceutical active ingredients. As a key building block, this chemical serves as an essential intermediate in the manufacturing process of anticoagulant medications. Our facility produces this compound under strict quality control standards to ensure consistency and reliability for downstream pharmaceutical applications. We understand the precision required in medicinal chemistry and deliver materials that meet rigorous industry specifications.

Technical Specifications

ParameterValue
CAS Number38560-30-4
Molecular FormulaC11H12N2O3
Molecular Weight220.225
AppearanceYellow powder
Assay≥98.0%
Density1.3±0.1 g/cm3
Boiling Point480.9±28.0 °C at 760 mmHg
Flash Point244.7±24.0 °C

Chemical Properties and Stability

This nitrophenyl-substituted piperidone derivative exhibits stable chemical characteristics suitable for multi-step organic synthesis. The presence of the nitro group on the phenyl ring provides specific reactivity profiles that are leveraged during reduction and coupling reactions. Proper handling ensures the integrity of the molecular structure throughout the storage and transportation phases. Our manufacturing process optimizes the crystalline structure to enhance solubility and reaction efficiency in subsequent synthesis steps. Users should adhere to standard laboratory safety protocols when handling this material to maintain optimal performance.

Industrial Applications

The primary application of 1-(4-Nitrophenyl)piperidin-2-one lies in the pharmaceutical sector, specifically as a precursor for Apixaban synthesis. This anticoagulant API requires high purity intermediates to ensure the safety and efficacy of the final medication. Beyond this specific use, the compound serves as a valuable scaffold in medicinal chemistry research for developing novel therapeutic agents. Our production capabilities support both large-scale commercial manufacturing and research-scale requirements. We work closely with process chemists to ensure the material fits seamlessly into existing synthetic routes.

Quality Assurance and Packaging

Quality is paramount in pharmaceutical intermediate supply. Each batch undergoes comprehensive testing using advanced analytical techniques such as HPLC and NMR to verify identity and purity. We provide a Certificate of Analysis (COA) with every shipment to document compliance with specified parameters. Packaging is designed to protect the material from moisture and light degradation. Standard packaging includes 25 kg drums, but we offer flexible solutions based on customer logistics and volume requirements. Storage recommendations include keeping the product in a cool, ventilated area away from incompatible substances.

Why Choose Our Supply

  • Consistent high purity levels exceeding 98 percent for reliable synthesis outcomes
  • Global manufacturing capabilities ensuring stable supply chains
  • Comprehensive technical support and documentation provided
  • Flexible packaging options tailored to client needs
  • Strict adherence to international quality and safety standards

Partner with us for dependable access to critical pharmaceutical intermediates. Our commitment to quality and service supports your production goals and regulatory compliance needs.