(2S)-1-Amino-3-chloro-2-propanol Hydrochloride

Product Overview

(2S)-1-Amino-3-chloro-2-propanol Hydrochloride is a critical chiral building block extensively utilized in the pharmaceutical industry, specifically serving as a key intermediate in the synthesis of Linezolid. This advanced organic compound is characterized by its specific stereochemistry, which is essential for ensuring the biological activity and efficacy of the final antibiotic product. Our manufacturing process adheres to strict quality control protocols to deliver material with high enantiomeric purity and consistent performance.

As a leading global manufacturer, we understand the stringent requirements of API production. This hydrochloride salt offers improved stability and handling properties compared to its free base form, making it ideal for large-scale industrial synthesis. The compound is designed to facilitate efficient coupling reactions while minimizing side products, thereby optimizing the overall yield of the pharmaceutical manufacturing process.

Technical Specifications

Quality and consistency are paramount in pharmaceutical supply chains. Our production facilities are equipped with state-of-the-art analytical instrumentation to verify every batch against rigorous specifications. The following table outlines the standard technical parameters for this product:

Industrial Applications

The primary application of (2S)-1-Amino-3-chloro-2-propanol Hydrochloride is in the production of Linezolid, an oxazolidinone antibiotic used to treat serious Gram-positive bacterial infections. The chiral center at the 2-position is vital for the drug's mechanism of action, inhibiting bacterial protein synthesis. Using a high-purity intermediate ensures that the final API meets pharmacopoeial standards such as USP, EP, or ChP.

Beyond Linezolid, this chemical serves as a versatile synthon in medicinal chemistry for developing other novel therapeutic agents requiring a chlorohydrin amine structure. Researchers and process chemists value this material for its reactivity profile and compatibility with various protection and deprotection strategies commonly employed in multi-step organic synthesis.

Quality Assurance and Safety

We are committed to providing products that meet international safety and quality standards. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing batch-specific test results. Our quality management system ensures traceability from raw materials to finished goods. Proper storage in a cool, ventilated area is recommended to maintain product integrity over time. We offer flexible packaging options, including 25 kg drums, to accommodate both pilot-scale research and commercial manufacturing needs.