1-Benzyl-4-Methylpiperidin-3-One
- CAS No.32018-96-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 1-Benzyl-4-Methylpiperidin-3-One (CAS 32018-96-5) designed for pharmaceutical synthesis. Reliable supply for Tofacitinib production.
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Product Overview
1-Benzyl-4-Methylpiperidin-3-One is a specialized organic compound widely recognized for its critical role in the synthesis of advanced pharmaceutical agents. As a key piperidinone derivative, this chemical serves as an essential building block in the development of kinase inhibitors and other therapeutic molecules. Our facility produces this intermediate under strict quality control standards to ensure consistency and reliability for downstream pharmaceutical manufacturing processes. The compound features a stable piperidine ring structure substituted with benzyl and methyl groups, providing unique reactivity profiles suitable for complex organic synthesis routes.
Technical Specifications
We maintain rigorous testing protocols to guarantee that every batch meets or exceeds industry standards for pharmaceutical intermediates. The following table outlines the key physical and chemical properties verified through our quality assurance laboratory using HPLC and NMR spectroscopy.
| Parameter | Value |
|---|---|
| CAS Number | 32018-96-5 |
| Molecular Formula | C13H17NO |
| Molecular Weight | 203.280 g/mol |
| Appearance | White to off-white powder |
| Assay | ≥98.0% |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 302.9±35.0 °C at 760 mmHg |
| Flash Point | 128.1±15.5 °C |
Industrial Applications
This intermediate is primarily utilized in the pharmaceutical sector for the synthesis of targeted therapeutic agents. Notably, it serves as a crucial precursor in the manufacturing pathway of Tofacitinib, a well-known Janus kinase (JAK) inhibitor used in the treatment of autoimmune conditions. The high purity level of our 1-Benzyl-4-Methylpiperidin-3-One ensures minimal impurity carryover into final active pharmaceutical ingredients (APIs), thereby facilitating smoother regulatory approval processes for our clients. Beyond this specific application, the compound is valuable for research and development teams exploring novel heterocyclic chemistry and medicinal chemistry programs focused on nitrogen-containing scaffolds.
Quality Assurance And Manufacturing
Our production facility adheres to international quality management systems to deliver consistent product performance. Each batch undergoes comprehensive analysis including identity confirmation, purity assessment, and residual solvent testing. We provide a Certificate of Analysis (COA) with every shipment to document compliance with specified parameters. Our manufacturing process is optimized for scalability, allowing us to meet both laboratory-scale research demands and large-scale commercial production requirements. We prioritize safety and environmental responsibility throughout the synthesis and packaging stages.
Storage And Handling
To maintain product integrity, 1-Benzyl-4-Methylpiperidin-3-One should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must remain tightly sealed when not in use to prevent degradation or contamination. Standard industrial safety precautions apply during handling, including the use of appropriate personal protective equipment such as gloves and safety goggles. The material is packaged in 25 kg drums by default, though custom packaging solutions are available to suit specific logistical needs. Global shipping capabilities ensure timely delivery to research centers and manufacturing plants worldwide.
