1-Benzylpiperidin-3-one Hydrochloride
- CAS No.40114-49-6
- GradeIndustrial / Pharmaceutical
- Availabilityβ In Stock
High purity 1-Benzylpiperidin-3-one hydrochloride designed for pharmaceutical synthesis. Reliable intermediate for Tofacitinib production with full quality documentation.
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Product Overview
1-Benzylpiperidin-3-one hydrochloride is a specialized organic compound widely utilized in the pharmaceutical industry as a critical building block. This chemical intermediate plays a pivotal role in the synthesis of complex active pharmaceutical ingredients, specifically serving as a key precursor in the manufacturing process of Tofacitinib. Our facility ensures that every batch meets rigorous international standards for purity and consistency, making it an ideal choice for large-scale production and research development projects.
The hydrochloride salt form enhances the stability and solubility of the compound, facilitating smoother reaction pathways during multi-step synthesis. We understand the importance of reliability in the supply chain for medicinal chemistry. Therefore, our production lines are optimized to deliver consistent quality while maintaining competitive lead times for global clients seeking dependable raw materials.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 1-Benzylpiperidin-3-one hydrochloride |
| CAS Number | 40114-49-6 |
| Molecular Formula | C12H15NO |
| Molecular Weight | 189.254 |
| Appearance | Off-white to light yellow powder |
| Assay | ≥95.0% |
| Melting Point | 170-176°C |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 294.6±33.0 °C at 760 mmHg |
Industrial Applications
This compound is primarily employed as an intermediate in the synthesis of Janus kinase (JAK) inhibitors. Its structural properties allow for efficient functionalization, enabling chemists to construct the necessary piperidine core found in various therapeutic agents. Beyond Tofacitinib, this building block is valuable for researchers exploring novel neurological therapeutics and advanced organic synthesis pathways where piperidine derivatives are required.
- Pharmaceutical API Synthesis
- Medicinal Chemistry Research
- Process Development for JAK Inhibitors
- Custom Organic Synthesis Projects
Quality Assurance and Storage
Quality control is paramount in our manufacturing process. Each lot undergoes comprehensive testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure transparency and compliance with your internal quality standards.
To maintain optimal stability, the product should be stored in a cool, ventilated place away from direct sunlight and moisture. We offer flexible packaging options, including 25 kg drums, and can accommodate custom packaging requirements based on specific logistical needs. Our commitment to safety and quality ensures that this intermediate arrives in perfect condition, ready for immediate use in your production facilities.
