1-Boc-2-[4-(2-Pyridinyl)benzylidene]hydrazine
- CAS No.198904-85-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 1-Boc-2-[4-(2-pyridinyl)benzylidene]hydrazine (CAS 198904-85-7), a critical intermediate for advanced antiviral and proteasome inhibitor APIs.
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Product Overview
1-Boc-2-[4-(2-Pyridinyl)benzylidene]hydrazine is a high-value, protected hydrazine derivative widely employed as a key building block in the synthesis of complex pharmaceutical active ingredients. With a molecular formula of C17H21N3O2 and a molecular weight of 299.37 g/mol, this compound features a tert-butoxycarbonyl (Boc) protecting group and a conjugated pyridinylbenzylidene moiety, offering excellent reactivity control and stability during multi-step organic syntheses.
Specifications
| Molecular Formula | C17H21N3O2 |
|---|---|
| Molecular Weight | 299.37 g/mol |
| Density | 1.17 g/cm³ |
| Melting Point | 74–77 °C |
| Refractive Index | 1.555 |
| Appearance | Off-white to white powder |
| Purity (HPLC) | ≥99% |
| Water Content (KF) | ≤0.5% |
Industrial Applications
This compound serves as a strategic intermediate in the manufacture of several high-profile therapeutic agents. It is specifically utilized in synthetic routes toward advanced antiviral and oncology APIs, including those structurally related to protease and proteasome inhibitors. Its robust chemical architecture enables precise functionalization in late-stage transformations, making it indispensable in modern medicinal chemistry campaigns.
- Enables efficient construction of nitrogen-containing heterocyclic scaffolds
- Compatible with standard deprotection and coupling protocols in solid- and solution-phase synthesis
- Supplied under strict GMP-aligned quality control for reproducible batch performance
Handling and Storage
Store in a tightly sealed container in a cool, dry place away from direct sunlight, heat sources, and moisture. For industrial use only—handle in accordance with local regulatory guidelines for fine chemical intermediates.
