Intermediates

1-Bromo-2,3-Difluorobenzene

  • CAS No.38573-88-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

1-Bromo-2,3-Difluorobenzene is a high-purity fluorinated aromatic intermediate essential for pharmaceutical synthesis. Available as a colorless liquid with ≥99.0% purity for industrial scaling.

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Product Technical Details

Product Overview

1-Bromo-2,3-Difluorobenzene is a specialized fluorinated aromatic compound widely recognized for its critical role in organic synthesis and medicinal chemistry. As a key building block, this substance facilitates the construction of complex molecular architectures required in the development of advanced pharmaceutical agents. Our manufacturing process ensures exceptional consistency, delivering a colorless liquid with high chemical integrity suitable for demanding research and production environments.

The presence of both bromine and fluorine substituents on the benzene ring provides unique reactivity profiles, enabling diverse transformation pathways such as cross-coupling reactions. This versatility makes it an indispensable resource for chemists aiming to introduce specific halogenated motifs into target molecules. We prioritize quality at every stage, from raw material sourcing to final packaging, to guarantee performance in your synthesis workflows.

Technical Specifications

To support rigorous quality control protocols, we provide comprehensive analytical data for every batch. The following table outlines the standard physical and chemical properties associated with this product. Our facilities adhere to strict manufacturing standards to ensure these parameters are met or exceeded consistently.

ParameterSpecification
CAS Number38573-88-5
Molecular FormulaC6H3BrF2
Molecular Weight192.99 g/mol
AppearanceColorless liquid
Purity≥99.0%
Density1.724 g/cm3
Boiling Point234 °C (765 mmHg)
Flash Point142 °F
Refractive Index1.509

Industrial Applications

This fluorinated intermediate is primarily utilized in the synthesis of pharmaceutical compounds. Its structural characteristics allow it to serve as a precursor for various bioactive molecules, including those used in therapeutic areas requiring precise halogen substitution. The stability of the carbon-fluorine bond combined with the reactivity of the carbon-bromine bond offers synthetic flexibility that is highly valued in process chemistry.

  • Used as a critical starting material for multi-step organic synthesis.
  • Enables efficient cross-coupling reactions such as Suzuki or Buchwald processes.
  • Supports the development of novel active pharmaceutical ingredients (APIs).
  • Suitable for large-scale manufacturing due to robust supply chain capabilities.

Quality Assurance and Safety

We understand that reliability is paramount in chemical procurement. Each production lot undergoes stringent testing using advanced chromatographic methods to verify purity and identity. A Certificate of Analysis (COA) is available upon request, providing full transparency regarding batch-specific data. Our commitment to safety extends to packaging and storage recommendations.

To maintain product stability, store in a tightly closed container within a cool, dry, and well-ventilated area. Ensure the storage location is away from incompatible substances to prevent unintended reactions. We offer flexible packing options, including 25kg drums, to accommodate various production scales while ensuring safe transport globally. Partner with us for a reliable supply of high-performance chemical intermediates designed to meet your industrial needs.