1-Bromo-2,4,5-Trifluorobenzene
- CAS No.327-52-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 1-Bromo-2,4,5-trifluorobenzene (CAS 327-52-6) designed for advanced organic synthesis and pharmaceutical intermediate applications.
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Product Overview
1-Bromo-2,4,5-Trifluorobenzene is a highly specialized fluorinated aromatic compound that serves as a critical building block in modern chemical synthesis. Characterized by its unique substitution pattern, this aryl bromide offers exceptional reactivity for cross-coupling reactions and nucleophilic substitutions. Our facility produces this compound under strict quality control standards to ensure consistent performance in downstream applications. The presence of multiple fluorine atoms enhances the metabolic stability and lipophilicity of final products, making it a preferred choice for medicinal chemistry and agrochemical development.
As a leading global manufacturer, we understand the importance of purity and reliability in supply chains. This product is synthesized using advanced catalytic processes that minimize impurities and by-products. The resulting material exhibits superior physical properties, including a defined boiling point and optimal density, which facilitate easier handling and processing in industrial settings. Whether used for research-scale experimentation or large-scale production, our 1-Bromo-2,4,5-Trifluorobenzene meets the rigorous demands of professional chemists.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 327-52-6 |
| Molecular Formula | C6H2BrF3 |
| Molecular Weight | 210.98 g/mol |
| Appearance | Colorless to light yellow transparent liquid |
| Assay (Purity) | ≥99.0% |
| Moisture Content | ≤0.2% |
| Boiling Point | 144°C |
| Density | 1.802 g/cm3 |
| Refractive Index | 1.485 |
Industrial Applications
This fluorinated intermediate is extensively utilized in the preparation of complex organic molecules. Its primary function lies in serving as a precursor for pharmaceuticals, where fluorine substitution is often key to improving drug efficacy. Additionally, it finds application in the synthesis of agrochemicals, liquid crystals, and functional materials. The bromine atom provides a versatile handle for palladium-catalyzed coupling reactions, enabling the construction of diverse chemical architectures.
- Pharmaceutical intermediate synthesis for novel therapeutics
- Agrochemical precursor for crop protection agents
- Material science applications in polymer modification
- Research and development in organic fluorine chemistry
Quality Assurance And Storage
Every batch of 1-Bromo-2,4,5-Trifluorobenzene undergoes comprehensive analytical testing before release. We employ gas chromatography and other advanced techniques to verify assay levels and impurity profiles. A Certificate of Analysis (COA) is provided with each shipment to guarantee compliance with stated specifications. Our commitment to quality ensures that customers receive material that performs predictably in their specific processes.
Proper storage is essential to maintain the integrity of this chemical. It should be kept in a cool, ventilated area away from direct sunlight and heat sources. Containers must remain tightly sealed to prevent moisture absorption and oxidation. We recommend standard safety protocols during handling, including the use of appropriate personal protective equipment. For bulk orders, we offer flexible packaging solutions, including 200 kg drums, tailored to meet logistical requirements and ensure safe global transportation.
