1-Bromo-2,5-difluorobenzene
- CAS No.399-94-0
- GradeIndustrial / Pharmaceutical
- Availabilityβ In Stock
High-purity 1-Bromo-2,5-difluorobenzene (CAS 399-94-0) designed for advanced organic synthesis. Available in bulk quantities with strict quality control.
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Product Overview
1-Bromo-2,5-difluorobenzene is a highly specialized fluorinated aromatic compound that serves as a critical building block in modern chemical synthesis. As a key intermediate, this substance is extensively utilized in the development of pharmaceuticals, agrochemicals, and advanced functional materials. Our facility produces this compound under rigorous quality management systems to ensure consistent molecular integrity and high purity levels suitable for sensitive downstream reactions.
The presence of both bromine and fluorine substituents on the benzene ring provides unique reactivity profiles, making it an ideal candidate for cross-coupling reactions and nucleophilic substitutions. We understand the demanding requirements of research and industrial-scale production, which is why our manufacturing process focuses on minimizing isomeric impurities and maximizing yield stability.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 399-94-0 |
| Molecular Formula | C6H3BrF2 |
| Molecular Weight | 192.99 g/mol |
| Appearance | Colorless liquid |
| Assay (Purity) | ≥99.0% |
| Moisture Content | ≤0.1% |
| Isomer Impurities | ≤0.2% |
| Density | 1.708 g/cm3 |
| Boiling Point | 58-59°C |
| Refractive Index | 1.508 |
Key Features and Advantages
- High Chemical Purity: Ensures minimal side reactions during complex synthesis routes.
- Low Isomer Content: Strictly controlled to meet demanding pharmaceutical standards.
- Stable Supply Chain: Reliable bulk production capacity for global distribution.
- Comprehensive Documentation: Full COA, MSDS, and technical support provided.
- Custom Packaging: Flexible options including 200 kg drums or tailored solutions.
Industrial Applications
This fluorinated intermediate is primarily employed in the synthesis of active pharmaceutical ingredients (APIs) where fluorine substitution enhances metabolic stability and bioavailability. It is also valuable in the creation of novel agrochemical compounds and liquid crystal materials. Researchers utilize this building block for palladium-catalyzed coupling reactions, enabling the construction of complex biaryl structures essential in drug discovery pipelines.
Safety and Storage Guidelines
Proper handling is essential to maintain product quality and ensure personnel safety. The material should be stored in a cool, well-ventilated area away from direct sunlight and incompatible substances. Containers must remain tightly sealed to prevent moisture absorption and oxidation. We recommend using appropriate personal protective equipment, including chemical-resistant gloves and safety goggles, during transfer operations. In case of spills, follow standard hazardous material containment procedures.
Quality Commitment
As a global manufacturer, we are committed to delivering excellence in every batch. Our quality control laboratory employs advanced analytical techniques such as GC and HPLC to verify specifications before shipment. We support our partners with timely logistics and technical expertise, ensuring that your production schedules remain uninterrupted. Contact our sales team for current bulk pricing and availability.
