Intermediates

1-Bromo-2-(bromomethyl)benzene

  • CAS No.3433-80-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 1-Bromo-2-(bromomethyl)benzene intermediate for organic synthesis. Reliable supply with COA.

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Product Technical Details

Product Overview

1-Bromo-2-(bromomethyl)benzene, also known commercially as 2-Bromobenzyl bromide, is a highly versatile organic intermediate utilized extensively in advanced chemical synthesis. Identified by CAS number 3433-80-5, this compound features a benzene ring substituted with both a bromine atom and a bromomethyl group in the ortho position. This unique structural configuration makes it an invaluable building block for constructing complex molecular architectures required in the pharmaceutical and agrochemical industries.

Our manufacturing process ensures that every batch meets rigorous international standards for purity and consistency. As a key reagent, it facilitates various transformation reactions, including nucleophilic substitutions and cross-coupling processes. The dual functionality of the molecule allows chemists to selectively functionalize different positions on the aromatic ring, providing significant flexibility in multi-step synthesis routes.

Technical Specifications

ParameterValue
Chemical Name1-Bromo-2-(bromomethyl)benzene
CAS Number3433-80-5
Molecular FormulaC7H6Br2
Molecular Weight249.93 g/mol
Purity (GC)≥99.0%
AppearanceYellowish to brownish red transparent liquid
Boiling Point129°C
Melting Point29-32°C
Density1.849 g/cm³
Refractive Index1.619

Quality Assurance and Industrial Applications

We understand that consistency is critical in industrial production. Therefore, our quality control team employs advanced gas chromatography (GC) techniques to verify purity levels exceeding 99.0%. Impurities such as 2-Bromotoluene are strictly controlled to remain below 0.5%, ensuring minimal side reactions during downstream processing. Moisture content is maintained at less than 0.1% to prevent hydrolysis during storage and usage.

  • Strict batch-to-batch consistency for reliable manufacturing outcomes.
  • Comprehensive documentation including Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS).
  • Optimized for use in pharmaceutical intermediate synthesis and fine chemical production.
  • Supported by a technical team capable of assisting with process optimization.

Storage and Handling

To maintain the stability and integrity of 1-Bromo-2-(bromomethyl)benzene, proper storage conditions are essential. The product should be stored in a cool, well-ventilated area away from direct sunlight and heat sources. Containers must be kept tightly sealed to prevent moisture absorption and oxidation. At lower temperatures, the material may crystallize into brownish red or off-white crystals, which is a normal physical phenomenon and does not affect quality.

Safety precautions should always be observed during handling. Personnel are advised to use appropriate personal protective equipment (PPE), including gloves and eye protection, to avoid skin contact or inhalation of vapors. In case of spills, standard chemical containment procedures should be followed immediately. We offer flexible packaging options, including 25 kg drums, and can accommodate custom packaging requirements to suit specific logistical needs for global shipment.