Intermediates

1-Bromo-2-Methoxy-3-Nitro-Benzene

  • CAS No.98775-19-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 1-Bromo-2-Methoxy-3-Nitro-Benzene (CAS 98775-19-0) for pharmaceutical synthesis. Reliable supply for Eltrombopag intermediates with ≥98% assay.

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Product Technical Details

Product Overview

1-Bromo-2-Methoxy-3-Nitro-Benzene is a specialized organic chemical intermediate designed for advanced pharmaceutical synthesis. This compound serves as a critical building block in the manufacturing of complex therapeutic agents, including key intermediates for Eltrombopag production. Our facility ensures strict quality control measures to deliver consistent molecular integrity and high purity levels suitable for large-scale industrial applications.

As a leading manufacturer, we understand the precision required in medicinal chemistry. This nitro-substituted bromo benzene derivative offers excellent reactivity for subsequent coupling and substitution reactions. The chemical structure provides a stable platform for introducing functional groups necessary for downstream API synthesis. Our production processes adhere to international safety and environmental standards, guaranteeing a reliable supply chain for global partners.

Key Specifications

ParameterSpecification
CAS Number98775-19-0
Molecular FormulaC7H6BrNO3
Molecular Weight232.031 g/mol
AppearancePale yellow to yellow powder
Assay (Purity)≥98.0%
Melting Point62-68°C
Loss on Drying≤1.0%
Density1.6±0.1 g/cm3
Boiling Point296.4±20.0 °C at 760 mmHg

Industrial Applications

This chemical intermediate is primarily utilized in the pharmaceutical sector for the synthesis of active pharmaceutical ingredients (APIs). Its specific substitution pattern makes it invaluable for constructing complex molecular architectures required in modern therapeutics. The compound is particularly noted for its role in the production pathway of Eltrombopag, a medication used to treat thrombocytopenia.

Beyond pharmaceutical uses, this substance supports research and development in organic chemistry laboratories. It serves as a reference standard for analytical method validation and process optimization. The high purity grade ensures minimal impurity carryover into final products, reducing purification costs and improving overall yield efficiency in multi-step synthesis routes.

Quality Assurance and Storage

Every batch undergoes rigorous testing using HPLC, NMR, and mass spectrometry to confirm identity and purity. We provide a comprehensive Certificate of Analysis (COA) with each shipment. Proper storage is essential to maintain chemical stability. The product should be kept in a cool, ventilated area away from direct sunlight and moisture. Containers must remain tightly sealed when not in use to prevent degradation or contamination.

We offer flexible packaging options, including standard 25 kg drums, customized according to client requirements. Our logistics team ensures safe and timely global delivery, complying with all hazardous material transportation regulations. For technical support, bulk pricing inquiries, or sample requests, please contact our sales department directly.