1-Bromo-4-(1,1-difluoroethyl)benzene
- CAS No.1000994-95-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 1-Bromo-4-(1,1-difluoroethyl)benzene (CAS 1000994-95-5) designed for advanced pharmaceutical synthesis. Available in bulk with strict quality control.
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Product Overview
1-Bromo-4-(1,1-difluoroethyl)benzene is a specialized fluorinated organic intermediate designed for use in complex pharmaceutical synthesis and advanced chemical research. As a key building block, this compound features a unique difluoroethyl substitution pattern on a bromobenzene core, offering distinct reactivity profiles for cross-coupling reactions and nucleophilic substitutions. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding industrial applications.
The incorporation of fluorine atoms into organic molecules is a critical strategy in modern medicinal chemistry to enhance metabolic stability and bioavailability. This product serves as a vital precursor for developing novel therapeutic agents. We maintain rigorous production standards to support global research and development pipelines requiring reliable access to fluorinated aryl bromides.
Technical Specifications
Quality assurance is paramount in the supply of chemical intermediates. Each batch undergoes comprehensive testing using gas chromatography and other analytical methods to verify composition and purity. The physical properties are tightly controlled to ensure performance consistency in downstream synthesis processes.
| Parameter | Value |
|---|---|
| CAS Number | 1000994-95-5 |
| Molecular Formula | C8H7BrF2 |
| Molecular Weight | 221.04 g/mol |
| Appearance | Colorless to Yellow clear liquid |
| Assay (GC) | ≥98.0% |
| Density | 1.495 g/cm3 |
| Boiling Point | 80-82°C |
| Flash Point | 82°C |
| Refractive Index | 1.503 |
Industrial Applications
This fluorinated intermediate is primarily utilized in the synthesis of pharmaceutical compounds where specific electronic and steric properties are required. The bromine functionality allows for versatile transformation via palladium-catalyzed coupling reactions, while the difluoroethyl group imparts favorable lipophilicity and stability characteristics to the final molecule.
- Pharmaceutical intermediate synthesis for novel drug candidates.
- Construction of fluorinated aromatic scaffolds in organic chemistry.
- Research and development of advanced functional materials.
- Custom synthesis projects requiring high-purity aryl bromides.
Quality Control and Assurance
Our facility operates under strict quality management systems to guarantee product integrity. We provide a Certificate of Analysis (COA) with every shipment, detailing batch-specific test results. Our technical team is available to support customers with documentation and regulatory compliance information required for their internal quality audits.
Storage and Handling
To maintain stability and safety, 1-Bromo-4-(1,1-difluoroethyl)benzene should be stored in a cool, ventilated area away from direct sunlight and heat sources. Containers must be kept tightly closed when not in use to prevent moisture absorption or contamination. Appropriate personal protective equipment should be worn during handling to ensure safety in accordance with standard laboratory and industrial hygiene practices.
Packaging and Logistics
We offer flexible packaging solutions to meet diverse customer needs. Standard packaging includes 200 kg drums, but custom packaging configurations are available upon request. Our logistics network ensures secure and timely global delivery, maintaining product condition throughout transit. Contact our sales team for detailed shipping information and bulk pricing options tailored to your project requirements.
