1-Bromo-4-(difluoromethoxy)benzene
- CAS No.5905-69-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 1-Bromo-4-(difluoromethoxy)benzene (CAS 5905-69-1) is a premium fluorinated intermediate designed for complex organic synthesis. Available in bulk with strict quality control.
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Product Overview
1-Bromo-4-(difluoromethoxy)benzene is a specialized fluorinated aromatic compound that serves as a vital building block in modern organic chemistry. Characterized by the presence of a difluoromethoxy group attached to a bromobenzene backbone, this molecule offers unique reactivity profiles essential for constructing complex molecular architectures. Our facility produces this intermediate under stringent quality management systems to ensure consistency and reliability for downstream synthesis applications.
The incorporation of fluorine atoms into organic molecules is a strategic approach in medicinal and agrochemical research to enhance metabolic stability and lipophilicity. As a key precursor, this compound enables chemists to introduce these beneficial properties into larger structures efficiently. We prioritize industrial purity standards to support high-yield reactions and minimize purification burdens in subsequent synthetic steps.
Key Specifications
| Parameter | Value |
|---|---|
| CAS Number | 5905-69-1 |
| Molecular Formula | C7H5BrF2O |
| Molecular Weight | 223.015 g/mol |
| Appearance | Colorless transparent liquid |
| Assay (Purity) | ≥98.0% |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 205.4±30.0 °C at 760 mmHg |
| Flash Point | 92.6±8.8 °C |
| Refractive Index | 1.492 |
Industrial Applications
This fluorinated intermediate is primarily utilized in the synthesis of advanced pharmaceutical agents and agrochemical compounds. The bromine substituent provides a reactive handle for cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, allowing for the versatile formation of carbon-carbon and carbon-heteroatom bonds. Researchers leverage this reactivity to develop novel candidates with improved biological profiles.
Beyond pharmaceuticals, this compound finds application in the development of specialized materials and fine chemicals where fluorine substitution is required to modify physical properties. Our manufacturing process is optimized to deliver material suitable for scale-up from laboratory research to pilot plant operations. We support various synthetic routes and can provide technical documentation to assist in process development.
Quality Assurance and Safety
Quality is paramount in our production workflow. Each batch of 1-Bromo-4-(difluoromethoxy)benzene undergoes rigorous analytical testing, including GC or HPLC analysis, to verify purity levels meet or exceed the specified 98.0% threshold. A Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance with your internal quality standards.
Regarding safety and handling, this chemical should be stored in a cool, ventilated area away from incompatible substances such as strong oxidizers. Proper personal protective equipment, including gloves and eye protection, is recommended during handling to prevent exposure. We offer flexible packaging options, including standard 200 kg drums or custom configurations based on specific logistical requirements. Contact our sales team for detailed safety data sheets and bulk pricing information tailored to your project needs.
