1-Bromo-4-fluoro-2-nitrobenzene

Product Overview

1-Bromo-4-fluoro-2-nitrobenzene is a highly specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. As a key intermediate, this chemical facilitates the construction of complex molecular architectures required in the pharmaceutical and agrochemical sectors. Our manufacturing process ensures exceptional consistency and purity, making it an ideal choice for research and industrial scale production.

The presence of both bromine and fluorine substituents on the nitrobenzene ring provides unique reactivity profiles, allowing for selective nucleophilic aromatic substitution reactions. This versatility makes the compound indispensable for medicinal chemists developing new therapeutic agents. We adhere to rigorous quality standards to guarantee that every batch meets the demanding specifications of global chemical industries.

Technical Specifications

Physical and Chemical Properties

Understanding the physical properties of this intermediate is essential for safe handling and process optimization. The compound exhibits a density of 1.808 g/cm3, indicating a relatively heavy molecular structure due to the halogen substituents. It melts within a narrow range of 37-39°C, which facilitates easy processing in various solvent systems. The boiling point is recorded at 220.9±20.0 °C at 760 mmHg, ensuring stability under standard distillation conditions.

Safety parameters include a flash point of 87.4±21.8 °C, requiring standard precautions for flammable organic solids. The index of refraction is measured at 1.580, serving as a key identifier for quality control verification. These properties are consistently monitored to ensure batch-to-batch reproducibility.

Industrial Applications

• Pharmaceutical Synthesis: Used as a precursor for developing novel drug candidates involving fluorinated aromatic systems.
• Agrochemical Production: Employed in the manufacture of advanced pesticides and herbicides requiring specific substitution patterns.
• Fine Chemicals: Serves as a versatile reagent for creating specialized organic compounds in laboratory and pilot plant settings.
• Research and Development: Essential for academic and industrial research focused on nucleophilic aromatic substitution mechanisms.

Quality Assurance and Storage

We implement a comprehensive quality assurance program that includes raw material inspection, in-process control, and final product testing. Each shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with specified purity levels. Our facility maintains strict environmental controls to prevent contamination during production and packaging.

For optimal stability, store this product in a tightly closed container within a cool, dry, and well-ventilated area. It should be kept away from incompatible substances such as strong oxidizing agents and bases. Standard packaging involves 25kg drums, ensuring safe transport and handling. We support global logistics to deliver this critical intermediate to manufacturers worldwide efficiently.