Intermediates

1-Bromo-4-(trifluoromethoxy)benzene

  • CAS No.407-14-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade fluorinated aromatic intermediate designed for advanced organic synthesis and pharmaceutical R&D applications.

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Product Technical Details

Product Overview

1-Bromo-4-(trifluoromethoxy)benzene is a highly specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by the presence of both a bromine substituent and a trifluoromethoxy group on the benzene ring, this molecule offers unique reactivity profiles that are essential for constructing complex chemical architectures. The trifluoromethoxy moiety is particularly valued in medicinal chemistry and agrochemical development due to its ability to enhance metabolic stability, lipophilicity, and bioavailability of final active ingredients.

Our manufacturing process ensures that every batch meets rigorous international standards for purity and consistency. As a key intermediate, this compound facilitates various cross-coupling reactions, including Suzuki, Heck, and Buchwald-Hartwig aminations, making it indispensable for researchers and industrial chemists aiming to develop novel molecular entities.

Technical Specifications

We maintain strict quality control protocols to guarantee the performance of our chemical intermediates. The following table outlines the key physical and chemical properties associated with this product batch.

ParameterSpecification
CAS Number407-14-7
Molecular FormulaC7H4BrF3O
Molecular Weight241.01 g/mol
AppearanceColorless clear liquid
Purity (GC)≥99.0%
Density1.622 g/cm3
Boiling Point80°C
Refractive Index1.461

Industrial Applications

This fluorinated intermediate finds extensive utility across multiple high-value sectors. Its primary application lies in the synthesis of pharmaceutical APIs, where the introduction of fluorine atoms can significantly alter the pharmacokinetic properties of drug candidates. Additionally, it is widely used in the development of new pesticides and herbicides, contributing to more effective crop protection solutions.

  • Pharmaceutical Research and Development
  • Agrochemical and Pesticide Synthesis
  • Advanced Material Science and Polymers
  • Fluorinated Reagent Production

Quality Assurance and Storage

To preserve the integrity of 1-Bromo-4-(trifluoromethoxy)benzene, proper storage conditions are essential. The product should be kept in a cool, ventilated area away from direct sunlight and incompatible materials. We offer flexible packaging options, including standard 200 kg drums, or customized solutions based on specific client logistics requirements. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) to verify compliance with stated specifications.

Why Choose Our Fluorinated Intermediates

Our company is dedicated to establishing a complete fluorochemical products and technology platform. We provide convenient one-stop services ranging from raw material procurement to final quality control. By integrating fluorination technology research and development with robust production capabilities, we ensure a stable supply chain for our global partners. Whether you require bulk quantities for large-scale manufacturing or specialized grades for research purposes, our team is committed to delivering excellence in every transaction.