Intermediates

1-Bromo-8-fluorooctane

  • CAS No.593-12-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 1-Bromo-8-fluorooctane (CAS 593-12-4) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and chemical manufacturing.

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Product Technical Details

Product Overview

1-Bromo-8-fluorooctane is a specialized fluorinated alkyl halide serving as a critical building block in modern organic synthesis. This compound features a unique structure combining a reactive bromo group with a stable fluoro substituent at opposite ends of an octane chain. Such structural characteristics make it an invaluable reagent for introducing fluoroalkyl motifs into complex molecular architectures. Our manufacturing process ensures consistent quality and high purity, meeting the rigorous demands of pharmaceutical research and industrial chemical production.

As a versatile intermediate, this substance facilitates the creation of novel compounds with enhanced metabolic stability and lipophilicity. The presence of the fluorine atom often imparts desirable physicochemical properties to the final product, making this bromide an essential tool for medicinal chemists and process developers. We maintain strict adherence to international quality standards to guarantee performance in sensitive synthetic routes.

Key Physical and Chemical Properties

The physical characteristics of 1-Bromo-8-fluorooctane are optimized for handling and reactivity in various solvent systems. It presents as a colorless transparent liquid, indicating high levels of refinement and absence of colored impurities. The compound exhibits specific density and refractive index values that serve as key identity markers during quality control testing. Its boiling point allows for distillation purification when necessary, while the flash point indicates standard safety protocols for flammable liquids should be observed during storage and handling.

  • High chemical stability under standard storage conditions
  • Excellent solubility in common organic solvents
  • Reactive bromo terminus for nucleophilic substitution
  • Stable fluoro terminus for metabolic resistance
  • Consistent batch-to-batch reproducibility

Technical Specifications

ParameterSpecification
CAS Number593-12-4
Molecular FormulaC8H16BrF
Molecular Weight211.12 g/mol
AppearanceColorless transparent liquid
Purity (Assay)≥99.0%
Moisture Content≤0.05%
Density1.178 g/cm³
Boiling Point224.2 ºC
Refractive Index1.437

Industrial Applications

Primarily utilized as an organic synthesis intermediate, this fluorinated bromide finds extensive application in the development of pharmaceutical active ingredients. It is frequently employed in the synthesis of compounds requiring a specific carbon chain length with terminal functionalization. The fluoro group enhances the biological profile of candidate drugs, while the bromo group allows for further functionalization via cross-coupling or alkylation reactions. Beyond pharmaceuticals, it is used in agrochemical research and material science where fluorinated chains improve surface properties or stability.

Quality Assurance and Packaging

Every batch of 1-Bromo-8-fluorooctane undergoes comprehensive analytical testing including GC, HPLC, and NMR spectroscopy to verify identity and purity. We provide a Certificate of Analysis (COA) with each shipment to ensure transparency and compliance. The product is packaged in 200 kg drums or according to specific customer requirements to maintain integrity during transit. Storage recommendations include keeping the container in a cool, ventilated place away from direct sunlight and incompatible materials. Our global logistics network ensures timely delivery while maintaining all safety regulations for chemical transport.