Intermediates

1-Chloro-3-fluoro-2-(trifluoromethyl)benzene

  • CAS No.103889-37-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 1-Chloro-3-fluoro-2-(trifluoromethyl)benzene designed for advanced organic synthesis. Reliable supply with comprehensive quality documentation.

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Product Technical Details

Product Overview

1-Chloro-3-fluoro-2-(trifluoromethyl)benzene is a specialized fluorinated aromatic compound widely utilized in the pharmaceutical and agrochemical industries. This advanced intermediate features a unique substitution pattern that enhances its reactivity in cross-coupling reactions and nucleophilic substitutions. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding synthetic pathways.

As a key building block, this compound facilitates the introduction of fluorine and chlorine motifs into complex molecular structures. The presence of the trifluoromethyl group significantly improves metabolic stability and lipophilicity in downstream drug candidates. We maintain strict quality control protocols to guarantee batch-to-batch consistency for large-scale production needs.

Key Specifications

ParameterValue
Chemical Name1-Chloro-3-fluoro-2-(trifluoromethyl)benzene
CAS Number103889-37-8
Molecular FormulaC7H3ClF4
Molecular Weight198.545 g/mol
AppearanceColorless to light yellow transparent liquid
Assay≥98.0%
Density1.4±0.1 g/cm3
Boiling Point160.9±35.0 °C at 760 mmHg
Flash Point55.7±19.4 °C

Industrial Applications

This fluorinated benzene derivative serves as a critical intermediate in the synthesis of novel pharmaceutical APIs and agrochemical active ingredients. Its specific substitution pattern allows for selective functionalization, making it ideal for multi-step synthesis routes. Common applications include the production of kinase inhibitors, anti-inflammatory agents, and crop protection chemicals.

  • Pharmaceutical intermediate for targeted therapy development
  • Agrochemical synthesis for enhanced pest control agents
  • Material science applications requiring fluorinated aromatics
  • Custom organic synthesis for research and development

Quality Assurance and Safety

We adhere to international quality standards to ensure product safety and reliability. Each batch is accompanied by a Certificate of Analysis (COA) detailing purity and impurity profiles. Proper handling procedures are essential due to the chemical nature of fluorinated compounds. Users should consult safety data sheets before integration into laboratory or industrial processes.

Storage recommendations include keeping the material in a cool, ventilated area away from incompatible substances. Packaging options are flexible to meet specific logistical requirements, ensuring safe transport globally. Our technical support team is available to assist with application guidance and regulatory documentation.