1-Chloro-6-iodohexane
- CAS No.34683-73-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 1-Chloro-6-iodohexane (CAS 34683-73-3) is a versatile bifunctional alkylating agent widely used as an intermediate in organic synthesis and pharmaceutical research.
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Product Overview
1-Chloro-6-iodohexane (CAS 34683-73-3) is a color-variable, pale red to light yellow liquid featuring both chlorine and iodine functionalities on a six-carbon aliphatic chain. This bifunctional halogenated hydrocarbon serves as a critical building block in advanced organic synthesis due to its dual reactivity, enabling sequential nucleophilic substitution reactions. With a molecular weight of 246.52 g/mol and high assay purity (≥99%), it is particularly valued in the preparation of complex molecular architectures, including macrocyclic compounds, functionalized polymers, and specialty intermediates for agrochemical and pharmaceutical development.
Specifications
| Molecular Formula | C6H12ClI |
|---|---|
| Molecular Weight | 246.517 g/mol |
| Density | 1.623 g/cm³ |
| Boiling Point | 110°C |
| Flash Point | >230°F |
| Refractive Index | 1.5230 |
| Appearance | Pale red liquid (may appear light yellow depending on batch) |
| Assay | ≥99.0% |
| Moisture | ≤0.3% |
Industrial Applications
As a specialized aliphatic dihalide, 1-Chloro-6-iodohexane is primarily employed in research and industrial-scale organic synthesis. Its strategic use includes:
- Serving as a linker or spacer in the construction of dendrimers and telechelic polymers.
- Facilitating the synthesis of heterocyclic compounds through intramolecular cyclization.
- Acting as a precursor in the preparation of quaternary ammonium salts and phase-transfer catalysts.
- Enabling the introduction of C6 spacers with orthogonal reactivity in multi-step syntheses.
Due to its sensitivity to light and thermal degradation, strict storage protocols are required: keep refrigerated, protected from light, and under inert atmosphere when possible. Standard packaging is 200 kg per drum, with custom options available upon request to meet GMP or research-grade handling standards.
