1-(Cyclopropylcarbonyl)piperazine hydrochloride
- CAS No.1021298-67-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
Premium grade 1-(Cyclopropylcarbonyl)piperazine hydrochloride designed for pharmaceutical synthesis. High purity specification ensures optimal reaction yields for Olaparib production.
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Product Overview
1-(Cyclopropylcarbonyl)piperazine hydrochloride is a highly specialized pharmaceutical intermediate engineered for complex organic synthesis workflows. This compound serves as a critical building block in the manufacturing of advanced therapeutic agents, specifically within the kinase inhibitor class. Our production facility adheres to strict quality management systems to ensure consistent molecular integrity and batch-to-batch reproducibility. The hydrochloride salt form enhances stability and handling characteristics during downstream processing.
As a dedicated manufacturer, we understand the stringent requirements of modern drug development. This material is synthesized using optimized reaction pathways that minimize impurities and maximize yield. The resulting product offers superior solubility profiles and reactivity, making it an ideal candidate for scale-up operations in regulated environments. We prioritize transparency and provide comprehensive documentation to support your regulatory filings.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 1-(Cyclopropylcarbonyl)piperazine hydrochloride |
| CAS Number | 1021298-67-8 |
| Molecular Formula | C8H15ClN2O |
| Molecular Weight | 190.67 g/mol |
| Appearance | White powder |
| Purity | ≥98.0% |
| Melting Point | 177°C |
Industrial Applications
The primary application of this intermediate lies in the synthesis of Olaparib, a prominent poly (ADP-ribose) polymerase (PARP) inhibitor used in oncology treatments. The structural integrity of the cyclopropylcarbonyl group is essential for the biological activity of the final active pharmaceutical ingredient (API). Researchers and process chemists utilize this compound to construct the core piperazine scaffold required for target engagement.
Beyond oncology, piperazine derivatives are increasingly explored in various therapeutic areas including central nervous system disorders and infectious diseases. The versatility of this building block allows for diverse functionalization strategies. Our team works closely with clients to understand specific process requirements, offering technical support for reaction optimization and impurity profiling.
Quality Assurance and Advantages
- Consistent high purity levels exceeding 98 percent for reliable reaction outcomes.
- Comprehensive Certificate of Analysis (COA) provided with every shipment.
- Manufactured in compliance with international quality standards.
- Robust supply chain ensuring timely delivery for production schedules.
- Competitive bulk pricing structures for large-scale manufacturing partners.
- Dedicated customer support for technical inquiries and customization.
Storage and Packaging
To maintain optimal stability, this product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Standard packaging consists of 25 kg drums lined with protective materials to prevent contamination during transit. Custom packaging solutions are available upon request to accommodate specific logistical needs. We employ secure shipping methods to ensure the product arrives in perfect condition, ready for immediate use in your synthesis pipeline.
