Intermediates

1-Ethoxy-2,2-difluoroethanol

  • CAS No.148992-43-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 1-Ethoxy-2,2-difluoroethanol is a specialized fluorinated intermediate designed for pharmaceutical and agrochemical synthesis applications.

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Product Technical Details

Product Overview

1-Ethoxy-2,2-difluoroethanol, also known commercially as Difluoroacetaldehyde Ethyl Hemiacetal, represents a critical building block in modern organic synthesis. As a specialized fluorinated intermediate, this compound plays an indispensable role in the development of advanced pharmaceutical agents and novel agrochemical formulations. Our facility produces this reagent under strict quality control standards to ensure consistent molecular integrity and performance across diverse synthetic pathways.

The incorporation of fluorine atoms into organic molecules often enhances metabolic stability and bioavailability, making this ethanol derivative highly valued in medicinal chemistry. We supply this material to research institutions and industrial manufacturers who require reliable sources of fluorinated synthons for complex molecule construction.

Chemical Specifications

PropertySpecification
CAS Number148992-43-2
Molecular FormulaC4H8F2O2
Molecular Weight126.10 g/mol
Density1.145 g/cm3
Boiling Point85.1°C at 760 mmHg
Flash Point46.2°C
Refractive Index1.356
Vapor Pressure44.9 mmHg at 25°C
Storage ConditionsRefrigerator (2-8°C)

Industrial Applications

This fluorinated intermediate is primarily utilized in the synthesis of active pharmaceutical ingredients (APIs) and new material science projects. Its unique chemical structure allows for versatile functionalization, enabling chemists to introduce difluoro motifs into target molecules efficiently. Common application areas include:

  • Pharmaceutical research and development for novel therapeutics.
  • Agrochemical synthesis for next-generation pesticide formulations.
  • Development of fluorinated polymers and advanced materials.
  • Organic synthesis as a reliable difluoroacetaldehyde equivalent.

Quality Assurance and Handling

We are committed to establishing a complete fluorochemical products and technology platform to provide customers with convenient one-stop services. Every batch of 1-Ethoxy-2,2-difluoroethanol undergoes rigorous analytical testing to verify purity and composition. A Certificate of Analysis (COA) is provided with each shipment to guarantee compliance with specified parameters.

Proper handling is essential for safety and product stability. Due to its volatility and chemical nature, storage in a refrigerated environment is recommended to prevent degradation. Our logistics team ensures secure packaging and global shipping capabilities, maintaining product integrity from our manufacturing site to your laboratory. For bulk orders or technical inquiries regarding synthesis routes, our expert support team is available to assist with your specific project requirements.