Intermediates

1-Ethyl-4-piperidone

  • CAS No.3612-18-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 1-Ethyl-4-piperidone liquid for pharmaceutical synthesis. Reliable supply for licensed manufacturers with full documentation.

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Product Technical Details

Product Overview

1-Ethyl-4-piperidone represents a critical heterocyclic building block within the fine chemical and pharmaceutical sectors. Recognized by its CAS registry number 3612-18-8, this organic compound serves as a foundational intermediate for the synthesis of complex therapeutic agents. Our manufacturing process ensures high chemical integrity, making it an ideal choice for licensed pharmaceutical producers requiring reliable raw materials for multi-step organic synthesis.

As a ketone-substituted piperidine derivative, this material exhibits specific reactivity profiles that are essential for constructing nitrogen-containing heterocycles. The ethyl group at the nitrogen position provides steric and electronic properties that facilitate specific downstream transformations. We prioritize consistency in every batch, supporting large-scale production needs while adhering to strict quality management systems. Our global supply chain ensures timely delivery to research facilities and production plants worldwide.

Technical Specifications

Understanding the physicochemical properties is vital for process engineers and chemists planning reaction conditions. The following data reflects typical values obtained through rigorous analytical testing in our certified laboratories. These parameters are critical for determining storage conditions and reaction safety protocols.

ParameterValue
Chemical Name1-Ethyl-4-piperidone
CAS Number3612-18-8
Molecular FormulaC7H13NO
Molecular Weight127.18 g/mol
AppearanceClear to Yellowish Liquid
Purity≥99.0%
Density0.944 g/mL at 25°C
Boiling Point46-48°C at 1 mm Hg
Melting Point30-32°C
Refractive Indexn20/D 1.464
Flash Point156°F

Quality Assurance and Control

Quality is the cornerstone of our chemical supply chain. Each production lot undergoes comprehensive analysis using advanced chromatography and spectroscopy methods. We provide a Certificate of Analysis (COA) with every shipment, detailing impurity profiles and confirming compliance with agreed specifications. Our facility operates under stringent safety and environmental protocols to ensure product stability and handler safety.

  • Batch-to-batch consistency for reliable synthesis outcomes.
  • Low impurity levels to minimize downstream purification costs.
  • Secure packaging to prevent moisture absorption and degradation.
  • Full traceability from raw material sourcing to final dispatch.
  • Compliance with international shipping regulations for chemical goods.

Industrial Applications

This compound is primarily utilized as a key intermediate in the pharmaceutical industry. It plays a significant role in the synthesis pathway of specific antidepressant agents, including derivatives related to Paroxetine. Chemists value this building block for its reactivity in forming piperidine rings, which are prevalent motifs in bioactive molecules. Beyond pharmaceuticals, it may find use in agrochemical research and specialized organic synthesis projects requiring nitrogenous heterocycles. The high purity grade ensures minimal side reactions during critical coupling steps.

Storage and Handling

To maintain optimal quality, 1-Ethyl-4-piperidone should be stored in a cool, dry, and well-ventilated area. Containers must remain tightly closed when not in use to protect against moisture and strong light. Safety data sheets (SDS) should be consulted prior to handling to ensure appropriate personal protective equipment is worn during transfer and processing operations. Proper ventilation is required due to the volatility indicated by the boiling point data.