1-Fluoro-2,4-dinitrobenzene

Product Overview

1-Fluoro-2,4-dinitrobenzene, frequently recognized within the chemical industry as 2,4-Dinitrofluorobenzene or DNFB, stands as a critical aromatic compound utilized extensively in organic synthesis and pharmaceutical manufacturing. This specialized intermediate is characterized by its high reactivity in nucleophilic aromatic substitution reactions, making it an indispensable building block for the production of advanced therapeutic agents. Our facility ensures that every batch meets rigorous international standards, providing clients with a reliable source for complex chemical synthesis requirements.

As a leading global manufacturer, we understand the importance of consistency in pharmaceutical supply chains. This compound serves as a key precursor in the synthesis of various fluoroquinolone antibiotics, including notable medications such as Ciprofloxacin, Pefloxacin, and Difloxacin. The precision required in these downstream applications demands an intermediate of exceptional purity and stability, which our production processes are specifically engineered to deliver.

Physical and Chemical Properties

Understanding the physicochemical profile of 1-Fluoro-2,4-dinitrobenzene is essential for safe handling and effective integration into synthesis routes. The compound typically presents as a light yellow crystalline solid at standard ambient temperatures. It possesses a defined molecular structure with a formula of C6H3FN2O4 and a molecular weight of approximately 186.10 g/mol. The substance exhibits moderate solubility in water but dissolves readily in common organic solvents, facilitating its use in diverse reaction media.

Thermal stability is a key consideration for storage and processing. With a melting point ranging between 25 and 27 degrees Celsius, care must be taken to maintain appropriate storage conditions to prevent liquefaction or degradation. The boiling point is recorded at approximately 296 degrees Celsius under standard atmospheric pressure. Safety parameters indicate a flash point near 133 degrees Celsius, classifying it as a combustible material that requires separation from strong oxidizing agents and strong bases to maintain stability during storage and transport.

Technical Specifications

Quality assurance is paramount in our manufacturing process. We employ advanced analytical techniques to verify the composition and purity of every lot. The following table outlines the standard specification parameters for our premium grade 1-Fluoro-2,4-dinitrobenzene:

Industrial Applications

The primary utility of this chemical lies in its role as a pharmaceutical intermediate. It is specifically valued for its ability to introduce fluorine and nitro functional groups into molecular structures, which are critical for the biological activity of many modern antibiotics. Beyond antibiotic synthesis, it is historically known as Sanger's reagent, used in protein sequencing to identify N-terminal amino acids, although our current focus remains on large-scale industrial pharmaceutical applications.

Our clients utilize this material in the manufacturing process of veterinary and human medicines. The high industrial purity ensures that downstream reactions proceed with minimal side products, optimizing yield and reducing purification costs. We support various synthesis routes and can provide technical documentation to assist in process optimization.

Packaging and Storage

To ensure product integrity upon arrival, 1-Fluoro-2,4-dinitrobenzene is packaged in secure 25kg drums. Custom packaging solutions are available upon request to meet specific logistical requirements. Storage recommendations include keeping the container tightly closed in a cool, dry, and well-ventilated area. Protection from moisture and incompatible substances is essential to maintain the specified quality attributes over time. We provide a Certificate of Analysis (COA) with every shipment to verify compliance with stated specifications.