Intermediates

1-Fluoro-6-iodohexane

  • CAS No.373-30-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 1-Fluoro-6-iodohexane (CAS 373-30-8) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and material science applications.

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Product Technical Details

Product Overview

1-Fluoro-6-iodohexane is a specialized fluorinated alkylating agent that serves as a critical building block in modern organic chemistry. Manufactured under strict quality control standards, this compound features a unique structure combining a reactive iodine moiety with a stable fluorine terminus. This dual functionality makes it an invaluable reagent for introducing fluoroalkyl chains into complex molecular architectures. Our facility ensures consistent batch-to-batch reliability, catering to the demanding needs of research laboratories and industrial production lines alike.

As a premier global manufacturer, we prioritize purity and safety in every production run. The compound is synthesized using advanced halogen exchange techniques to minimize impurities and maximize yield. Whether utilized in the development of new materials or as a key intermediate in pharmaceutical research, 1-Fluoro-6-iodohexane provides the reactivity profile necessary for efficient synthetic routes.

Key Chemical Properties

The chemical structure of 1-Fluoro-6-iodohexane (C6H12FI) offers distinct advantages for synthetic chemists. The terminal iodine atom acts as an excellent leaving group, facilitating nucleophilic substitution reactions with high efficiency. Meanwhile, the fluorine atom at the opposite end of the hexyl chain imparts metabolic stability and lipophilicity to the final product, which is often desirable in medicinal chemistry and agrochemical development.

Physical characteristics include a high density and specific boiling point that allow for straightforward purification via distillation. The refractive index serves as a key quality indicator, ensuring the identity and purity of the liquid match theoretical values. These properties are rigorously tested to comply with international chemical standards.

Technical Specifications

ParameterValue
CAS Number373-30-8
Molecular FormulaC6H12FI
Molecular Weight230.06 g/mol
AppearanceColorless transparent liquid
Assay (Purity)≥99.0%
Moisture Content≤0.05%
Density1.515 g/cm3
Boiling Point202.7 °C
Flash Point75.9 °C
Refractive Index1.477

Industrial Applications

This fluorinated intermediate is widely employed across multiple sectors of the chemical industry. In pharmaceutical research, it is utilized for the synthesis of bioactive molecules where fluorine substitution enhances pharmacokinetic properties. It serves as a versatile linker in the construction of complex organic frameworks.

  • Organic synthesis intermediates for fine chemicals.
  • Building block for material science and polymer modification.
  • Reagent for introducing fluoroalkyl groups in medicinal chemistry.
  • Precursor for specialized agrochemical formulations.

Storage and Handling

To maintain optimal stability, 1-Fluoro-6-iodohexane should be stored in a cool, ventilated place away from direct sunlight and heat sources. Containers must be kept tightly closed to prevent moisture absorption and oxidation. Standard safety protocols for handling alkyl halides should be followed, including the use of appropriate personal protective equipment. We offer flexible packing options, including 200 kg drums, and can customize packaging according to specific customer requirements to ensure safe global transportation.