1-Fluoro-8-iodooctane
- CAS No.1189187-93-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 1-Fluoro-8-iodooctane (CAS 1189187-93-6) is a versatile bifunctional alkylating agent widely used as an intermediate in advanced organic synthesis.
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Product Overview
1-Fluoro-8-iodooctane is a high-purity, bifunctional halogenated aliphatic compound featuring both fluorine and iodine termini on an eight-carbon linear chain. This unique molecular architecture enables its strategic use as a building block in multi-step organic syntheses, particularly in the construction of complex molecular scaffolds requiring orthogonal reactivity. As a specialty intermediate, it supports the development of novel pharmaceuticals, agrochemicals, and functional materials through selective nucleophilic substitution or cross-coupling reactions.
Specifications
| Molecular Formula | C8H16FI |
|---|---|
| Molecular Weight | 258.12 g/mol |
| Appearance | Colorless transparent liquid |
| Assay | ≥99.0% |
| Moisture | ≤0.05% |
| Density | 1.4 ± 0.1 g/cm³ |
| Boiling Point | 244.8 ± 8.0 °C |
| Flash Point | 105.4 ± 2.6 °C |
| Refractive Index | 1.477 |
Industrial Applications
This compound serves primarily as a dual-functionalized intermediate in research and industrial-scale organic chemistry. Its iodine moiety offers excellent leaving-group capability for palladium-catalyzed couplings (e.g., Suzuki, Sonogashira), while the terminal fluorine provides metabolic stability or polarity modulation in target molecules. Key application areas include:
- Synthesis of long-chain fluorinated surfactants and polymers
- Preparation of heterobifunctional linkers for bioconjugation chemistry
- Construction of macrocyclic frameworks in medicinal chemistry
- Development of novel liquid crystals or electronic materials
Stored in a cool, well-ventilated area away from light and moisture, 1-Fluoro-8-iodooctane is typically supplied in 200 kg drums or customized packaging to meet GMP and regulatory standards for chemical intermediates.
