1-Fluoronaphthalene
- CAS No.321-38-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 1-Fluoronaphthalene liquid intermediate designed for pharmaceutical synthesis, including neurological therapeutics.
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Product Overview
1-Fluoronaphthalene is a premier fluorinated aromatic compound extensively utilized in modern organic synthesis and pharmaceutical manufacturing. As a critical building block, this chemical serves as a foundational element for constructing complex molecular structures required in advanced therapeutic developments. Our facility specializes in the production of high-grade fluorinated intermediates, ensuring that every batch meets rigorous international standards for purity and consistency.
This compound is characterized by its stable chemical structure and high reactivity in nucleophilic substitution reactions, making it an indispensable resource for medicinal chemists. The introduction of a fluorine atom into the naphthalene ring significantly enhances the metabolic stability and bioavailability of downstream pharmaceutical products. We maintain a robust supply chain to support large-scale industrial requirements while adhering to strict environmental and safety protocols.
Technical Specifications
| Parameter | Specification |
|---|---|
| Product Name | 1-Fluoronaphthalene |
| CAS Number | 321-38-0 |
| Molecular Formula | C10H7F |
| Molecular Weight | 146.16 g/mol |
| Appearance | Clear colorless liquid |
| Assay (GC) | ≥99.5% |
| Boiling Point | 215.0±0.0 °C at 760 mmHg |
| Melting Point | -13 °C |
| Density | 1.1±0.1 g/cm3 |
| Refractive Index | 1.606 |
Industrial Applications
The primary application of 1-Fluoronaphthalene lies in the pharmaceutical sector, where it acts as a key intermediate in the synthesis of neurological therapeutics. Specifically, it is utilized in the manufacturing pathways for agents such as Duloxetine, demonstrating its vital role in producing medications for central nervous system disorders. Beyond pharmaceuticals, this compound finds utility in agrochemical synthesis and materials science, where fluorinated aromatics are required to enhance product performance and durability.
Our clients benefit from a versatile chemical solution that integrates seamlessly into various synthesis routes. Whether used for research and development or full-scale commercial production, 1-Fluoronaphthalene provides the reliability needed for consistent output. We support our partners with detailed technical documentation to facilitate efficient process integration and regulatory compliance.
- High reactivity for efficient coupling reactions
- Superior purity levels minimizing downstream purification
- Stable supply chain for continuous manufacturing
- Comprehensive quality control testing
Storage and Safety Handling
Proper storage and handling are essential to maintain the integrity of 1-Fluoronaphthalene. The product should be stored in a cool, ventilated warehouse away from direct sunlight and sources of ignition. The storage temperature should not exceed 37 degrees Celsius to prevent degradation or pressure buildup. Containers must be kept tightly closed when not in use to avoid contamination and moisture absorption.
Safety is our paramount concern. This material is classified under Hazard Class 6.1 and requires careful handling by trained personnel. Appropriate personal protective equipment, including gloves and eye protection, must be worn during handling. In case of spillage, absorb with inert material and dispose of according to local hazardous waste regulations. We provide comprehensive Safety Data Sheets (SDS) and Certificates of Analysis (COA) with every shipment to ensure full transparency and safety compliance across your supply chain.
