1-Hydroxybenzotriazole Hydrate
- CAS No.123333-53-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
Premium grade 1-Hydroxybenzotriazole Hydrate designed for efficient peptide coupling and organic synthesis. Available in bulk with certified quality assurance.
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Product Overview
1-Hydroxybenzotriazole Hydrate is a highly specialized chemical intermediate widely recognized for its critical role in modern organic synthesis and peptide coupling reactions. As a stable hydrate form of HOBt, this compound offers enhanced safety profiles compared to its anhydrous counterparts while maintaining superior reactivity. Our manufacturing process ensures consistent molecular integrity, making it an essential reagent for pharmaceutical research and industrial scale production.
This compound functions primarily as a nucleophilic catalyst and additive in carbodiimide-mediated couplings. It effectively suppresses racemization during peptide bond formation, ensuring high optical purity of the final product. The hydrate form provides improved handling characteristics, reducing the risks associated with shock sensitivity often found in dry benzotriazole derivatives.
Technical Specifications
We adhere to strict quality control protocols to guarantee that every batch meets rigorous international standards. The following table outlines the key physical and chemical parameters verified through our internal laboratory testing.
| Parameter | Specification |
|---|---|
| CAS Number | 123333-53-9 |
| Molecular Formula | C6H5N3O |
| Appearance | White crystal powder |
| Purity (HPLC) | ≥99.0% |
| Melting Point | 155-158°C |
| Water Content | 11-14% |
| Packing | 25 kg/drum |
Industrial Applications
The versatility of 1-Hydroxybenzotriazole Hydrate extends across multiple sectors within the fine chemicals industry. Its primary application lies in the synthesis of complex peptides and proteins, where maintaining stereochemistry is paramount. Researchers and process chemists rely on this reagent to minimize side reactions and improve overall yields in amide bond formation.
Beyond peptide synthesis, it serves as a valuable building block in the production of various pharmaceutical intermediates. The high purity grade provided by our facility supports sensitive reaction pathways where impurities could compromise downstream processing. Whether used in laboratory scale discovery or large-scale manufacturing, this product delivers consistent performance.
Quality Assurance and Safety
Our commitment to quality is evidenced by the comprehensive Certificate of Analysis (COA) provided with each shipment. Every production lot undergoes thorough testing for identity, assay, and physical properties. We maintain full traceability from raw material sourcing to final packaging, ensuring compliance with global regulatory requirements.
Regarding safety, this material is classified under Hazard Class 4.1. Proper storage conditions are essential to maintain stability and safety. We recommend storing the product in a cool, ventilated area away from incompatible substances. Our packaging solutions are designed to protect the integrity of the hydrate during transit, ensuring it arrives in optimal condition for immediate use.
Why Choose Our Supply
- Consistent high purity levels exceeding 99.0%.
- Reliable bulk supply chain capable of meeting large demand.
- Competitive pricing structures for long-term partnerships.
- Technical support available for process optimization.
- Global shipping capabilities with secure packaging.
Selecting the right chemical partner is crucial for maintaining production efficiency. We stand ready to support your synthesis needs with premium grade 1-Hydroxybenzotriazole Hydrate, backed by decades of industry expertise and a commitment to excellence.
