Intermediates

1-Iodo-5-Fluoropentane

  • CAS No.373-18-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 1-Iodo-5-Fluoropentane (CAS 373-18-2) for use as a versatile halogenated building block in organic synthesis.

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Product Technical Details

Product Overview

1-Iodo-5-Fluoropentane (CAS 373-18-2) is a high-purity, bifunctional alkyl halide featuring both iodo and fluoro substituents at terminal positions of a linear pentane chain. This compound serves as a valuable intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures through selective nucleophilic substitution or cross-coupling reactions. Its dual-halogen functionality offers orthogonal reactivity, making it particularly useful in multi-step synthetic strategies within pharmaceutical and agrochemical R&D.

Specifications

Molecular FormulaC5H10FI
Molecular Weight216.04 g/mol
AppearanceColorless transparent liquid
Assay≥99.0%
Moisture≤0.05%
Density1.596 g/cm³
Boiling Point180.1°C
Flash Point65.7°C
Refractive Index1.478

Industrial Applications

As a specialty halogenated intermediate, 1-Iodo-5-Fluoropentane is primarily employed in research and development settings for:

  • Serving as a precursor in the synthesis of fluorinated heterocycles and bioactive molecules
  • Facilitating C–C bond formation via palladium-catalyzed cross-coupling protocols
  • Acting as an alkylating agent in medicinal chemistry campaigns
  • Supporting materials science applications requiring defined fluorine incorporation

Due to its reactive nature, this compound must be handled under inert atmosphere and stored in a cool, well-ventilated area away from light and moisture. Standard packaging is 200 kg per drum, with custom configurations available upon request to meet specific logistical or safety requirements.