Intermediates

1-Methoxy-3-Nitro-5-(Trifluoromethyl)Benzene

  • CAS No.328-79-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity fluorinated benzene intermediate designed for complex organic synthesis and pharmaceutical manufacturing processes.

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Product Technical Details

Product Overview

1-Methoxy-3-Nitro-5-(Trifluoromethyl)Benzene is a specialized fluorinated aromatic compound engineered for high-performance organic synthesis. As a critical building block in modern chemical manufacturing, this intermediate combines the reactivity of a nitro group with the metabolic stability and lipophilicity provided by the trifluoromethyl moiety. Our production facility adheres to strict quality management systems to ensure every batch meets rigorous purity standards suitable for downstream pharmaceutical and agrochemical applications.

The presence of the methoxy group allows for versatile functionalization, making this compound an ideal precursor for developing advanced molecular structures. We understand the importance of consistency in multi-step synthesis routes, which is why our manufacturing process focuses on minimizing impurities that could affect reaction yields or complicate purification stages.

Key Specifications

Quality control is paramount in the production of fine chemical intermediates. Each lot undergoes comprehensive analysis using advanced chromatographic and spectroscopic methods to verify identity and purity. The following table outlines the standard technical parameters for this product:

ParameterSpecification
CAS Number328-79-0
Molecular FormulaC8H6F3NO3
Molecular Weight221.13 g/mol
Assay (Purity)≥98.0%
Moisture Content≤0.2%
Melting Point36-38°C
Boiling Point246.9°C
Density1.392 g/cm3

Industrial Applications

This fluorinated intermediate serves as a vital component in the synthesis of various active pharmaceutical ingredients (APIs) and crop protection agents. The trifluoromethyl group is particularly valued in medicinal chemistry for enhancing bioavailability and metabolic stability of drug candidates. Researchers utilize this compound to introduce specific electronic and steric properties into complex molecular frameworks.

  • Pharmaceutical Synthesis: Used as a key starting material for developing novel therapeutic agents.
  • Agrochemical Development: Employed in the creation of herbicides and pesticides with improved environmental profiles.
  • Material Science: Applicable in the synthesis of specialized polymers and liquid crystals.
  • Custom Organic Synthesis: Available for bespoke research projects requiring high-purity fluorinated building blocks.

Storage and Handling

To maintain optimal quality, 1-Methoxy-3-Nitro-5-(Trifluoromethyl)Benzene should be stored in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. The container must remain tightly closed when not in use to prevent moisture absorption. We recommend following standard safety protocols for handling nitro compounds and fluorinated organics, including the use of appropriate personal protective equipment.

We offer flexible packaging solutions to meet diverse industrial needs, ranging from standard drums to customized containers based on client requirements. Our logistics team ensures secure global shipping with full documentation, including Certificates of Analysis (COA) and Safety Data Sheets (SDS). For bulk orders or technical inquiries regarding synthesis routes, our experienced support team is ready to assist.