Intermediates

1-Methyl-3-phenylpiperazine

  • CAS No.5271-27-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 1-Methyl-3-phenylpiperazine (CAS 5271-27-2) designed for pharmaceutical synthesis, specifically as a key intermediate for Mirtazapine production.

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Product Technical Details

Product Overview

1-Methyl-3-phenylpiperazine is a highly specialized organic compound widely recognized for its critical role in modern pharmaceutical synthesis and medicinal chemistry. As a key structural building block, this chemical intermediate facilitates the production of complex therapeutic agents with high efficiency. Our facility produces this compound under strict quality control protocols to ensure consistency and reliability for large-scale industrial applications. The molecular structure provides excellent reactivity, making it an indispensable component for medicinal chemists engaged in the development of neurological therapeutics and other advanced pharmaceutical formulations.

We understand the demanding requirements of the global pharmaceutical industry. Therefore, every batch undergoes rigorous analytical testing using state-of-the-art equipment such as HPLC and GC to verify identity and purity. This commitment to excellence ensures that downstream synthesis processes proceed smoothly without unexpected impurities affecting the final API quality. Our production capabilities are designed to meet global demand while maintaining the highest standards of safety, environmental responsibility, and regulatory compliance.

Technical Specifications

The following table outlines the standard physical and chemical properties associated with this product. Please note that specific parameters may vary slightly based on production batches, but all shipments comply with the agreed-upon specifications and international quality standards.

ParameterValue
CAS Number5271-27-2
Molecular FormulaC11H16N2
Molecular Weight176.258
AppearanceWhite to yellowish powder
Assay≥98.0%
Melting Point58-61°C
Moisture Content≤0.5%
Density1.0±0.1 g/cm3
Boiling Point280.3±25.0 °C

Pharmaceutical Applications

This compound serves primarily as a vital intermediate in the synthesis of Mirtazapine, a well-known pharmaceutical agent used in the treatment of depression and related mood disorders. The high purity level of our 1-Methyl-3-phenylpiperazine ensures efficient reaction yields and minimizes the formation of side products during the manufacturing process. Beyond this specific application, it is also utilized in various research and development projects focused on creating novel piperazine derivatives for potential therapeutic use.

Chemists value this material for its stability and predictable reactivity profiles. Whether used in pilot-scale experiments or full commercial production, the consistency of our supply allows for reliable process scaling. We support both custom synthesis requirements and standard bulk orders to accommodate diverse project timelines and research needs. Our technical team is available to provide guidance on optimal storage and handling procedures to maximize product performance.

Quality Assurance and Packaging

Quality is the cornerstone of our operations. Each drum is sealed to prevent moisture absorption and contamination during transit. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing the test results for identity, assay, and physical properties. Our packaging options include standard 25 kg drums, with flexibility to meet specific customer logistics requirements and safety regulations.

  • Stored in a cool, ventilated place to maintain chemical stability.
  • Protected from direct sunlight and excessive heat sources.
  • Compatible with standard hazardous material shipping regulations.
  • Long shelf life when stored under recommended conditions.
  • Regular quality audits to ensure continuous improvement.

Partnering with us means gaining access to a reliable supply chain backed by decades of industry experience. We are committed to supporting your production goals with timely deliveries, competitive pricing, and responsive technical support. Contact our sales team today to discuss your specific requirements and request a quote.