1-Methylazepan-4-one
- CAS No.19869-42-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 1-Methylazepan-4-one (CAS 19869-42-2) designed for pharmaceutical synthesis. Reliable intermediate for Azelastine production with strict quality control.
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Product Overview
1-Methylazepan-4-one is a specialized heterocyclic compound widely recognized for its critical role in the synthesis of advanced pharmaceutical agents. As a key building block, this chemical entity features a seven-membered azepane ring structure with a ketone functional group, providing excellent reactivity for downstream organic transformations. Our manufacturing process ensures high consistency and purity, making it an ideal choice for research laboratories and large-scale production facilities focused on antihistamine development.
We understand the stringent requirements of the pharmaceutical industry. Therefore, our production facilities adhere to rigorous quality management systems. Each batch undergoes comprehensive analytical testing to verify identity, potency, and impurity profiles. This commitment to excellence ensures that our clients receive materials that meet or exceed international pharmacopoeia standards, facilitating smoother regulatory filings and production runs.
Technical Specifications
The following table outlines the typical physical and chemical properties of our standard grade material. Please note that specific parameters may vary slightly based on the salt form or custom requirements agreed upon during the procurement process.
| Parameter | Specification |
|---|---|
| Chemical Name | 1-Methylazepan-4-one |
| CAS Number | 19869-42-2 |
| Molecular Formula | C7H14ClNO (Hydrochloride) |
| Molecular Weight | 163.645 g/mol |
| Appearance | Yellow-brown powder |
| Assay (Purity) | ≥95.0% |
| Loss on Drying | ≤2.0% |
| Single Impurity | ≤1.5% |
| Total Impurities | ≤5.0% |
| Boiling Point | 196.4°C at 760 mmHg |
| Flash Point | 67.2°C |
Industrial Applications
The primary application of 1-Methylazepan-4-one lies in the pharmaceutical sector, specifically serving as a vital intermediate in the synthesis of Azelastine hydrochloride. Azelastine is a well-established antihistamine used globally for the treatment of allergic rhinitis and conjunctivitis. The structural integrity of this ketone intermediate is crucial for maintaining the efficacy and safety profile of the final active pharmaceutical ingredient (API).
Beyond its primary use, this compound serves as a valuable building block in medicinal chemistry for constructing diverse nitrogen-containing heterocycles. Researchers utilize its reactive carbonyl group for various condensation and reduction reactions, enabling the development of novel therapeutic candidates. Our team supports custom synthesis projects, offering flexibility in scale and specification to meet unique research demands.
Quality Assurance and Safety
Quality is the cornerstone of our operation. We employ advanced analytical techniques, including HPLC, GC, and NMR spectroscopy, to validate every production lot. A Certificate of Analysis (COA) is provided with each shipment, detailing the test results against our strict internal specifications. This transparency allows our partners to maintain their own quality standards without compromise.
Regarding safety, this material should be handled in accordance with standard laboratory safety protocols. It is recommended to use appropriate personal protective equipment (PPE) such as gloves and safety goggles during handling. The material should be stored in a cool, ventilated area away from incompatible substances to ensure stability and safety over time.
Packaging and Logistics
We offer flexible packaging solutions to accommodate various supply chain needs. The standard packaging configuration is 25 kg per drum, ensuring secure transport and easy handling in industrial settings. However, we understand that different projects require different scales. Therefore, we can customize packaging according to specific customer requirements, including smaller quantities for R&D purposes or bulk containers for manufacturing.
Our logistics network is optimized for global delivery. We work with trusted freight forwarders to ensure timely and secure shipment to destinations worldwide. Whether you require air freight for urgent samples or sea freight for bulk orders, our team coordinates the entire process to minimize lead times and maximize efficiency. Contact our sales team today to discuss your requirements and request a competitive bulk price quote.
