Intermediates

1-O-Acetyl-2,3,5-Tri-O-Benzoyl-Beta-D-Ribofuranose

  • CAS No.6974-32-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity protected ribose intermediate essential for nucleoside analog synthesis. Available in bulk quantities with full COA and custom packaging options for pharmaceutical research.

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Product Technical Details

Product Overview

1-O-Acetyl-2,3,5-Tri-O-Benzoyl-Beta-D-Ribofuranose is a highly specialized protected sugar derivative widely utilized in the field of advanced organic synthesis. This compound features a ribofuranose core where the hydroxyl groups at the 2, 3, and 5 positions are protected by benzoyl groups, while the anomeric position is acetylated. This specific protection pattern is critical for controlling stereochemistry during the construction of complex nucleoside structures. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal starting material for demanding pharmaceutical applications.

The stability provided by the benzoyl protecting groups allows chemists to perform various transformations on the sugar moiety without unwanted side reactions. This level of molecular precision is essential when developing active pharmaceutical ingredients where structural integrity directly impacts biological activity. We produce this intermediate under strict quality control protocols to meet the rigorous standards required by the global fine chemicals market.

Technical Specifications

We maintain comprehensive quality assurance measures for every production lot. The following table outlines the key physical and chemical parameters guaranteed for this product. Our analytical team verifies each parameter using validated methods such as High-Performance Liquid Chromatography (HPLC) to ensure purity levels exceed industry norms.

ParameterSpecification
AppearanceWhite to almost white crystalline powder
Assay (HPLC)≥99.0%
Loss on Drying≤0.5%
Heavy Metals≤20ppm
Molecular FormulaC28H24O9
Molecular Weight504.49 g/mol
Melting Point128-130°C

Industrial Applications

This protected ribose derivative serves as a fundamental building block in the synthesis of nucleoside analogs. These analogs are frequently investigated for their potential in oncology therapeutics and antiviral research. The compound is particularly valuable in routes requiring the formation of glycosidic bonds with high stereoselectivity. By providing a stable platform, it facilitates the efficient construction of complex molecular architectures needed for next-generation medicines.

Research laboratories and pharmaceutical manufacturers rely on this intermediate for developing anti-neoplastic agents and other specialized therapeutics. Its high purity minimizes the need for extensive downstream purification, thereby improving overall process efficiency and reducing production costs. Whether used in early-stage drug discovery or scale-up manufacturing, this material supports the creation of vital medical treatments.

Quality Assurance and Storage

Quality is the cornerstone of our operation. Each batch is accompanied by a Certificate of Analysis (COA) detailing all test results. We employ advanced analytical instrumentation to verify identity, purity, and impurity profiles. Our facility adheres to international safety and quality management systems to ensure product reliability. We offer flexible packaging solutions, including 25 kg drums, and can accommodate custom requirements based on specific logistical needs.

Proper storage is essential to maintain the integrity of this chemical. It should be kept in a cool, ventilated area away from direct sunlight and moisture. Containers must remain tightly sealed when not in use to prevent hydrolysis or degradation. With a flash point of approximately 264°C, standard chemical handling precautions apply. Our global logistics network ensures timely delivery while maintaining appropriate storage conditions throughout transit.