Intermediates

1-phenyl-5-pyridin-2-ylpyridin-2-one

  • CAS No.381725-50-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used primarily in the synthesis of Perampanel. Available in bulk with strict quality control and comprehensive documentation.

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Product Technical Details

Product Overview

1-phenyl-5-pyridin-2-ylpyridin-2-one is a specialized organic compound recognized for its critical role in modern pharmaceutical synthesis. As a key building block, this substance serves as an essential intermediate in the production of advanced neurological therapeutics. Our facility produces this chemical under rigorous quality management systems to ensure consistency and reliability for downstream API manufacturing. The compound features a distinct biaryl ketone structure that facilitates specific coupling reactions required in complex drug synthesis pathways.

We understand the demands of the pharmaceutical supply chain. Therefore, every batch undergoes extensive analytical testing to verify structural integrity and purity levels. This commitment to excellence makes our product a preferred choice for research institutions and commercial manufacturing plants seeking dependable raw materials for high-value drug production.

Technical Specifications

Our production process adheres to strict international standards. The following table outlines the key physical and chemical properties verified during our quality control procedures. These parameters ensure the material performs predictably during subsequent synthetic steps.

ParameterSpecification
CAS Number381725-50-4
Molecular FormulaC16H12N2O
Molecular Weight248.279 g/mol
AppearanceOff-white to light yellow powder
Assay (Purity)≥98.0%
Density1.2±0.1 g/cm3
Boiling Point444.8±45.0 °C at 760 mmHg
Flash Point222.8±28.7 °C

Application & Usage

This chemical is primarily utilized as a strategic intermediate in the synthesis of Perampanel, a notable antiepileptic agent. The high purity grade we supply is designed to minimize impurities that could affect the yield or safety profile of the final active pharmaceutical ingredient. Chemists value this compound for its stability and reactivity profile, which aligns perfectly with standard industrial coupling protocols.

  • Ideal for large-scale API manufacturing processes.
  • Compatible with various organic synthesis routes.
  • Supports the production of neurological therapeutic agents.
  • Suitable for research and development in medicinal chemistry.

Quality Assurance & Packaging

Quality is the cornerstone of our operation. Each drum is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. We employ advanced chromatography and spectroscopy methods to confirm identity and assay. Regarding logistics, the product is packaged in 25 kg drums to ensure safety during transit, though custom packaging solutions are available upon request to meet specific client requirements.

Storage recommendations include keeping the material in a cool, ventilated area away from direct sunlight and moisture. Proper handling ensures the longevity and stability of the chemical properties. Our global distribution network ensures timely delivery to support your production schedules without interruption.