Intermediates

1-(Tetrahydro-2-furoyl)piperazine

  • CAS No.63074-07-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used in Terazosin synthesis. Available in bulk with strict quality control and global logistics support.

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Product Technical Details

Product Overview

1-(Tetrahydro-2-furoyl)piperazine is a specialized organic compound widely recognized within the pharmaceutical industry for its critical role as a key building block in medicinal chemistry. This piperazine derivative serves as an essential intermediate in the synthesis of various therapeutic agents, most notably contributing to the production of alpha-adrenergic blockers. Our manufacturing process ensures that every batch meets rigorous international standards, providing chemical researchers and production facilities with a reliable source of high-quality material for complex organic synthesis pathways.

As a trusted global manufacturer, we understand the importance of consistency in pharmaceutical supply chains. This compound is engineered to facilitate efficient reaction kinetics during downstream processing, ensuring optimal yields for final active pharmaceutical ingredients. Our facility adheres to strict quality management systems to guarantee that the chemical integrity of the product remains uncompromised from synthesis to delivery.

Technical Specifications

To support our partners in quality control and regulatory compliance, we provide comprehensive specification data for every shipment. The following table outlines the standard parameters for our commercial grade material, which can be customized upon request for specific research requirements.

ParameterSpecification
CAS Number63074-07-7
Molecular FormulaC9H16N2O2
Molecular Weight184.24 g/mol
AppearanceWhite or off-white powder
Purity≥98.0%
Total Impurities<0.5%
Packing Options25kg cardboard drum or custom

Physical and Chemical Properties

Understanding the physicochemical profile of 1-(Tetrahydro-2-furoyl)piperazine is vital for safe handling and process optimization. The compound exhibits a density of approximately 1.147 g/cm3, which influences its behavior in solution during reaction phases. With a boiling point around 140 degrees Celsius under reduced pressure, it demonstrates thermal stability suitable for various synthesis conditions. The flash point ranges between 120 to 125 degrees Celsius, necessitating standard safety precautions during storage and transport to prevent ignition risks.

The refractive index, measured between 1.5195 and 1.5215, serves as a key identifier for purity verification using optical methods. These properties collectively ensure that the material performs predictably in industrial-scale reactors, minimizing variability in the production of downstream pharmaceutical products such as Terazosin Hydrochloride.

Industrial Applications

The primary application of this chemical lies in the pharmaceutical sector, specifically as a precursor in the manufacturing of antihypertensive medications. It acts as a crucial intermediate in the synthesis route for Terazosin Hydrochloride, a drug used to treat high blood pressure and benign prostatic hyperplasia. Beyond this specific use, the versatile piperazine structure allows for potential applications in developing other neurological therapeutics and complex organic molecules.

  • Key intermediate for alpha-blocker synthesis
  • Suitable for large-scale pharmaceutical manufacturing
  • Compatible with standard organic synthesis protocols
  • Supports custom research and development projects

Quality Assurance and Storage

We prioritize product stability and longevity through advanced packaging and storage protocols. The material should be stored in a cool and dry environment, ideally between 2 to 8 degrees Celsius, to maintain its chemical potency. Containers must be well-closed to protect against moisture absorption and exposure to strong light or heat, which could degrade the quality over time. Each batch is accompanied by a Certificate of Analysis (COA), ensuring full traceability and compliance with customer specifications.

Our logistics network supports global shipping, ensuring that bulk orders arrive safely and on schedule. Whether you require standard packing in 25kg drums or specialized containers according to specific requirements, our team is equipped to handle diverse logistical needs while maintaining the highest safety standards throughout the supply chain.