Intermediates

1-Trifluoromethyl-1,2-Benziodoxol-3(1H)-One

  • CAS No.887144-94-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity trifluoromethylation reagent designed for advanced organic synthesis and pharmaceutical R&D. Reliable supply with comprehensive quality documentation.

Request Bulk Pricing

Product Technical Details

Product Overview

1-Trifluoromethyl-1,2-Benziodoxol-3(1H)-One is a specialized hypervalent iodine reagent widely recognized for its efficiency in trifluoromethylation reactions. This compound serves as a critical source of the trifluoromethyl group (CF3), enabling chemists to introduce fluorine atoms into complex organic molecules with high precision. As fluorine-containing structures become increasingly vital in modern medicinal chemistry and material science, the demand for stable and reactive trifluoromethylating agents has grown significantly. Our product is synthesized under strict quality control protocols to ensure consistent performance in laboratory and industrial settings.

The unique structure of this benziodoxolone derivative provides enhanced stability compared to traditional trifluoromethyl sources, reducing handling risks while maintaining high reactivity. It is particularly valued in the development of new pharmaceutical intermediates, agrochemicals, and advanced functional materials where fluorine incorporation improves metabolic stability and lipophilicity.

Technical Specifications

ParameterSpecification
Product Name1-Trifluoromethyl-1,2-Benziodoxol-3(1H)-One
CAS Number887144-94-7
Molecular FormulaC8H4F3IO2
Molecular Weight316.02 g/mol
Melting Point150-158 °C
AppearanceWhite to off-white powder
Storage Conditions2-8 °C, protected from light
Purity≥ 98.0% (HPLC)

Industrial Applications

This reagent is extensively utilized across multiple high-tech sectors. In pharmaceutical research and development, it facilitates the synthesis of fluorinated active pharmaceutical ingredients (APIs) and key intermediates. The introduction of trifluoromethyl groups often enhances the bioavailability and binding affinity of drug candidates. Additionally, the compound is employed in the development of new pesticides, where fluorination improves environmental stability and efficacy.

Beyond life sciences, this material supports the creation of new organic materials and polymers. Researchers leverage its properties to develop compounds with unique electronic or optical characteristics. Our fluorochemical platform ensures that customers receive materials suitable for both small-scale discovery and larger process development stages.

Quality Assurance and Storage

Maintaining the integrity of hypervalent iodine reagents requires careful handling and storage. Our product is packaged in moisture-resistant containers and stored under controlled temperatures between 2-8 °C to prevent degradation. Each batch undergoes rigorous analytical testing, including HPLC and NMR analysis, to verify identity and purity. Customers are provided with a comprehensive Certificate of Analysis (COA) upon request, ensuring full traceability and compliance with internal quality standards.

Supply Chain Capability

As a dedicated manufacturer within the fluorochemical industry, we offer a complete technology platform for fluorine-containing products. Our capabilities span from raw material procurement to final product quality control. We are committed to providing convenient one-stop services for global clients, ensuring timely delivery and competitive bulk pricing. Whether for academic research or industrial production, our team supports customers with technical expertise and reliable supply chain management.