1-(Trifluoromethylthio)pyrrolidine-2,5-dione
- CAS No.183267-04-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 1-(Trifluoromethylthio)pyrrolidine-2,5-dione serves as a critical electrophilic trifluoromethylthiolating reagent for advanced pharmaceutical and agrochemical synthesis.
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Product Overview
1-(Trifluoromethylthio)pyrrolidine-2,5-dione, also known as N-(Trifluoromethylthio)succinimide, is a highly specialized fluorinating reagent designed for the introduction of the trifluoromethylthio (SCF3) group into organic molecules. This compound plays a pivotal role in modern medicinal chemistry and agrochemical development, where the incorporation of fluorine atoms significantly enhances metabolic stability, lipophilicity, and bioavailability of the final active ingredients. Our facility ensures that every batch meets rigorous international standards for purity and consistency, supporting complex synthetic pathways in research and industrial production.
Technical Specifications
| Property | Specification |
|---|---|
| Chemical Name | 1-(Trifluoromethylthio)pyrrolidine-2,5-dione |
| CAS Number | 183267-04-1 |
| Molecular Formula | C5H4F3NO2S |
| Molecular Weight | 199.15 g/mol |
| Density | 1.6 ± 0.1 g/cm3 |
| Boiling Point | 145.1 ± 50.0 °C at 760 mmHg |
| Vapor Pressure | 4.9 ± 0.3 mmHg at 25°C |
| Refractive Index | 1.486 |
| Appearance | White to off-white powder |
Industrial Applications
This advanced fluorinating agent is extensively utilized across multiple high-value sectors. In pharmaceutical research, it serves as a key building block for synthesizing novel drug candidates, particularly in oncology and central nervous system therapeutics where fluorine substitution is critical. In agrochemicals, it contributes to the development of next-generation pesticides and fungicides with improved environmental profiles and efficacy. Additionally, it is employed in the creation of new materials with specific electronic or surface properties.
- Pharmaceutical API synthesis and drug discovery
- Agrochemical intermediate production for pesticides
- Fluorine-containing material research and development
- Electrophilic trifluoromethylthiolation reactions
Quality Assurance and Supply
Shanghai Fluorine Technology is committed to establishing a complete fluorochemical products and technology platform. We provide convenient one-stop services ranging from raw material procurement to final quality control. Our manufacturing process adheres to strict safety and environmental protocols, ensuring industrial purity levels suitable for scale-up. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) to verify identity and purity. We offer competitive bulk pricing and reliable global logistics to support your supply chain needs efficiently.
