Intermediates

10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepine

  • CAS No.3159-07-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepine (CAS 3159-07-7), a critical intermediate for advanced pharmaceutical synthesis.

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Product Technical Details

Product Overview

10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepine is a high-value heterocyclic compound widely employed as a key building block in the synthesis of complex pharmaceutical active ingredients. With a molecular formula of C13H9NOS and a molecular weight of 227.282 g/mol, this compound features a fused tricyclic structure that serves as a strategic scaffold in medicinal chemistry. It is primarily utilized in the industrial-scale production of second-generation antipsychotic agents, functioning as an essential precursor in regulated, GMP-compliant API manufacturing workflows.

Specifications

Molecular FormulaC13H9NOS
Molecular Weight227.282 g/mol
Melting Point265°C
Density1.3 ± 0.1 g/cm³
Boiling Point309.2 ± 12.0 °C at 760 mmHg
Flash Point140.8 ± 19.6 °C
Vapour Pressure0.0 ± 0.7 mmHg at 25°C
Refractive Index1.667
AppearanceWhite to Off-white powder
Assay≥98.0%

Industrial Applications

This compound is exclusively used as a chemical intermediate in the multi-step synthesis of regulated pharmaceutical substances under strict quality control protocols. It is not intended for direct human or veterinary use. Its primary role lies in enabling the efficient construction of dibenzothiazepine-based molecular architectures, which are integral to certain neurological therapeutics developed through advanced organic synthesis pathways. As a non-formulation-grade material, it supports robust, scalable manufacturing processes in compliance with international regulatory standards.

  • High chemical stability under standard storage conditions
  • Consistent batch-to-batch purity for reliable process reproducibility
  • Suitable for large-scale cGMP-compliant API production
  • Supplied with full analytical documentation including COA