Intermediates

1,3-Dichloro-5-fluorobenzene

  • CAS No.1435-46-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 1,3-Dichloro-5-fluorobenzene (CAS 1435-46-7) designed for pharmaceutical synthesis. Reliable supply with ≥99.0% purity.

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Product Technical Details

Product Overview

1,3-Dichloro-5-fluorobenzene is a highly valued fluorinated aromatic compound widely utilized in the fine chemical and pharmaceutical industries. As a critical building block, this substance serves as an essential intermediate for the synthesis of complex organic molecules. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research and development teams as well as large-scale production facilities. The presence of both chlorine and fluorine substituents on the benzene ring provides unique reactivity profiles, enabling diverse chemical transformations required in modern drug discovery and agrochemical formulations.

We understand the importance of reliability in the supply chain. Therefore, every batch of 1,3-Dichloro-5-fluorobenzene undergoes rigorous quality control testing to meet international standards. Our facility is equipped with advanced analytical instruments to verify composition and purity, ensuring that customers receive materials that perform predictably in their specific applications. Whether you are developing new therapeutic agents or optimizing existing synthesis routes, our product provides the foundational quality necessary for success.

Technical Specifications

ParameterValue
Chemical Name1,3-Dichloro-5-fluorobenzene
CAS Number1435-46-7
Molecular FormulaC6H3Cl2F
Molecular Weight164.99 g/mol
AppearanceColorless to pale yellow liquid
Purity≥99.0%
Density1.403 g/cm3
Flash Point54.8°C
Refractive Index1.519
Packing25kg/drum

Industrial Applications

This fluorinated intermediate is primarily employed in the pharmaceutical sector as a key precursor for active pharmaceutical ingredients (APIs). Its specific substitution pattern allows for selective nucleophilic aromatic substitution reactions, which are vital for constructing complex molecular architectures. Beyond pharmaceuticals, it finds utility in the production of specialized agrochemicals and functional materials where halogenated benzene derivatives are required. The high purity grade we supply minimizes side reactions, thereby improving overall yield and reducing downstream purification costs for our clients.

Researchers value this compound for its stability and reactivity balance. It serves as a versatile synthon in cross-coupling reactions and other catalytic processes. By integrating this material into your workflow, you can achieve greater efficiency in synthetic pathways. Our technical team is available to provide guidance on handling and integration into various formulation processes, ensuring optimal results for your specific project requirements.

Quality Assurance and Safety

Safety and compliance are paramount in our operations. 1,3-Dichloro-5-fluorobenzene should be stored in a tightly closed container within a cool, dry, and well-ventilated area. It is crucial to keep the material away from incompatible substances to prevent hazardous reactions. Our packaging is designed to maintain integrity during transit, reducing the risk of contamination or leakage. We provide comprehensive documentation, including Certificates of Analysis (COA), with every shipment to verify that the product meets all specified criteria.

Our commitment to excellence extends beyond the product itself. We offer robust logistical support to ensure timely delivery globally. With a focus on sustainability and safety, our manufacturing processes adhere to strict environmental regulations. Choosing us as your partner means gaining access to a reliable supply of high-quality chemical intermediates backed by decades of industry expertise. Contact us today to discuss your volume requirements and receive a competitive quote for bulk orders.