1,7-Dichloro-4-methoxy-isoquinoline
- CAS No.630423-36-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 1,7-dichloro-4-methoxy-isoquinoline (CAS 630423-36-8), a key pharmaceutical intermediate for antiviral drug synthesis.
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Product Overview
1,7-Dichloro-4-methoxy-isoquinoline is a high-value heterocyclic building block widely employed in the synthesis of complex pharmaceutical active ingredients. With a molecular formula of C10H7Cl2NO and a molecular weight of 228.075 g/mol, this compound serves as a critical intermediate in the production of advanced therapeutics, including the antiviral agent Asunaprevir (CAS 630420-16-5). Our product is manufactured under stringent quality control protocols to ensure consistent performance in demanding synthetic applications.
Specifications
| Molecular Formula | C10H7Cl2NO |
|---|---|
| Molecular Weight | 228.075 g/mol |
| Density | 1.4 ± 0.1 g/cm³ |
| Boiling Point | 355.7 ± 37.0 °C at 760 mmHg |
| Flash Point | 168.9 ± 26.5 °C |
| Vapour Pressure | 0.0 ± 0.8 mmHg at 25 °C |
| Refractive Index | 1.631 |
| Appearance | Off-white to brown powder |
| Assay | ≥98.0% |
Industrial Applications
This isoquinoline derivative is primarily utilized as a synthetic intermediate in the pharmaceutical industry. Its unique chloro- and methoxy-substituted scaffold enables selective functionalization for constructing bioactive molecules targeting viral proteases and other therapeutic pathways. Key advantages include:
- High chemical stability under standard handling conditions
- Excellent reactivity in cross-coupling and nucleophilic substitution reactions
- Consistent batch-to-batch purity for reliable scale-up
- Compliance with international regulatory standards for pharmaceutical intermediates
Stored in a cool, well-ventilated area away from incompatible materials, 1,7-dichloro-4-methoxy-isoquinoline is typically supplied in 25 kg drums or customized packaging to meet client-specific logistics requirements.
