Intermediates

18-Crown-6

  • CAS No.17455-13-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

18-Crown-6 is a high-efficiency phase transfer catalyst and complexing agent used in fine organic synthesis and electronic materials. Available in bulk with ≥99.0% purity.

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Product Technical Details

Product Overview

18-Crown-6, chemically known as 1,4,7,10,13,16-Hexaoxacyclooctadecane, stands as a premier macrocyclic polyether within the field of advanced organic synthesis. This cyclic ether is renowned for its exceptional ability to coordinate with alkali metal cations, particularly potassium ions, due to the precise match between its cavity size and the ionic radius of the metal. As a leading manufacturer, we supply high-purity 18-Crown-6 designed to meet the rigorous demands of pharmaceutical intermediates, fine chemical production, and materials science research.

Our production process ensures consistent quality and reliability. The compound functions primarily as a phase transfer catalyst, facilitating reactions between reagents in immiscible phases by solubilizing ionic species in organic solvents. This capability significantly enhances reaction rates and yields in nucleophilic substitutions and other critical transformations. Whether utilized in laboratory-scale research or industrial-scale manufacturing, our 18-Crown-6 delivers superior performance and reproducibility.

Key Specifications

We adhere to strict quality control protocols to guarantee the integrity of every batch. The following table outlines the standard physical and chemical properties associated with our premium grade 18-Crown-6. Custom specifications may be available upon request for specific industrial applications.

ParameterSpecification
AppearanceWhite to almost white crystalline powder
CAS Number17455-13-9
Molecular FormulaC12H24O6
Molecular Weight264.32 g/mol
Purity (Assay)≥99.0%
Water Content≤0.1%
Melting Point38-41°C
Heavy Metals≤0.002%

Industrial Applications

The versatility of 18-Crown-6 makes it indispensable across multiple high-tech sectors. In organic synthesis, it serves as a powerful complexing agent that activates nucleophiles by stripping away cationic counterions. This property is extensively leveraged in the production of pharmaceutical intermediates and specialty polymers. Additionally, it acts as an efficient extraction agent for the separation and purification of noble metals and rare earth elements, supporting the mining and refining industries.

Beyond chemical synthesis, 18-Crown-6 finds significant application in the electronics industry. It is utilized as a component in ion-conducting materials and liquid crystal display (LCD) manufacturing. Its ability to facilitate ion transport makes it valuable in the development of solid-state electrolytes for batteries and sensors. Furthermore, in analytical chemistry, it is employed for the enrichment, separation, and masking of specific ions, ensuring precise measurement and detection in complex matrices.

Quality Assurance And Storage

Every shipment is accompanied by a Certificate of Analysis (COA) verifying compliance with our factory standards. We recommend storing 18-Crown-6 in a ventilated, dry environment at low temperatures, ideally between 0-5°C. It is crucial to prevent long-term storage without proper monitoring to avoid the potential generation of peroxides. Our packaging options include 25 kg drums, with flexibility to accommodate specific customer logistics requirements. Contact our sales team for detailed safety data sheets and bulk pricing information.