Intermediates

1H-1,2,4-Triazole

  • CAS No.288-88-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 1H-1,2,4-triazole (CAS 288-88-0), a key heterocyclic intermediate for triazole-class agrochemicals and pharmaceutical building blocks.

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Product Technical Details

Product Overview

1H-1,2,4-Triazole (CAS 288-88-0) is a versatile five-membered heterocyclic compound featuring three nitrogen atoms. It serves as a fundamental structural motif in the synthesis of numerous triazole-derived active ingredients widely used in modern crop protection formulations. With high chemical stability and reactivity, this compound is indispensable in the industrial-scale production of conazole fungicides.

Specifications

Molecular FormulaC₂H₃N₃
Molecular Weight69.065 g/mol
AppearanceWhite needle-like crystals
Assay≥99.0%
Water Content≤0.5%
Melting Point119–121 °C (lit.)
Boiling Point260.0 ± 9.0 °C at 760 mmHg
Density1.3 ± 0.1 g/cm³
Water Solubility1250 g/L at 20 °C
Storage ConditionStore at 0–5 °C in a cool, dry, and well-ventilated area with container tightly closed

Industrial Applications

1H-1,2,4-Triazole is primarily employed as a critical synthetic intermediate in the manufacture of a broad spectrum of triazole-based agricultural fungicides. Its core structure enables the construction of bioactive molecules with enhanced systemic activity and environmental persistence. Key downstream products include:

  • Triadimefon (CAS 43121-43-3)
  • Triadimenol (CAS 55219-65-3)
  • Bitertanol (CAS 55179-31-2)
  • Tebuconazole (CAS 107534-96-3)
  • Difenoconazole (CAS 119446-68-3)
  • Propiconazole (CAS 60207-90-1)
  • Hexaconazole (CAS 79983-71-4)
  • Cyproconazole (CAS 94361-06-5)

Beyond agrochemicals, it also finds utility in pharmaceutical research as a scaffold for developing novel therapeutic agents targeting fungal infections and other microbial diseases. As a non-formulation-ready chemical, it is classified strictly as a synthesis intermediate rather than a functional end-product.

Supplied in standard 25 kg drums or customized packaging upon request, our 1H-1,2,4-triazole meets stringent quality control standards for global B2B supply chains.