Intermediates

1H-Imidazol-1-ylacetonitrile

  • CAS No.98873-55-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 1H-Imidazol-1-ylacetonitrile (CAS 98873-55-3) designed for pharmaceutical synthesis, specifically as a key intermediate for antifungal agents like Luliconazole.

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Product Technical Details

Product Overview

1H-Imidazol-1-ylacetonitrile is a specialized organic compound characterized by its imidazole ring structure coupled with a nitrile functional group. This chemical serves as a vital building block in modern medicinal chemistry, particularly within the realm of heterocyclic synthesis. Our facility produces this intermediate under strict quality control protocols to ensure consistency and reliability for downstream pharmaceutical applications. The compound is recognized for its stability and reactivity, making it an essential precursor in the development of various therapeutic agents.

As a leading global manufacturer, we understand the critical nature of supply chain integrity for pharmaceutical intermediates. Our production processes are optimized to deliver high purity levels while maintaining cost-effectiveness for bulk orders. This product is specifically engineered to meet the rigorous demands of organic synthesis laboratories and large-scale manufacturing plants focused on antifungal medication production.

Technical Specifications

We adhere to comprehensive analytical standards to guarantee the quality of every batch. The following table outlines the key physical and chemical properties along with our standard specification limits. Each shipment is accompanied by a Certificate of Analysis (COA) verifying these parameters.

ParameterSpecification
CAS Number98873-55-3
Molecular FormulaC5H5N3
Molecular Weight107.113 g/mol
AppearanceWhite to off-white powder
Assay (HPLC)98.0% - 102.0%
Density1.1 ± 0.1 g/cm3
Boiling Point329.7 ± 25.0 °C at 760 mmHg
Flash Point153.2 ± 23.2 °C
Loss on Drying≤ 0.5%
Total Impurities≤ 1.0%

Industrial Applications

The primary application of 1H-Imidazol-1-ylacetonitrile lies in the synthesis of advanced pharmaceutical compounds. It is most notably utilized as a key intermediate in the manufacturing process of Luliconazole, a potent antifungal agent used to treat skin infections. The unique chemical structure allows for efficient coupling reactions necessary to construct the final active pharmaceutical ingredient (API).

Beyond antifungal agents, this imidazole derivative finds utility in broader organic synthesis contexts where nitrogen-containing heterocycles are required. Researchers and process chemists value this material for its predictable reactivity profile, which facilitates smoother reaction pathways and higher overall yields in multi-step synthesis routes. Our team works closely with clients to ensure the material specifications align perfectly with their specific process requirements.

Quality Assurance and Storage

Quality assurance is the cornerstone of our manufacturing philosophy. Every batch undergoes rigorous testing using high-performance liquid chromatography (HPLC) and other analytical methods to confirm purity and identity. We maintain detailed records for full traceability from raw material sourcing to final packaging. This commitment ensures that our partners receive materials that consistently conform to factory standards and international expectations.

Proper storage is essential to maintain the integrity of the chemical. We recommend storing 1H-Imidazol-1-ylacetonitrile in a cool, ventilated place away from direct sunlight and moisture. The product is typically packaged in 25 kg drums, though we offer flexible packaging solutions tailored to customer logistics needs. By following these storage guidelines, users can ensure the material remains stable and ready for use in their synthesis operations.