Intermediates

1H-Pyrazole-1-carboxamidine Hydrochloride

  • CAS No.4023-02-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 1H-Pyrazole-1-carboxamidine Hydrochloride (CAS 4023-02-3) designed for pharmaceutical synthesis, specifically as a key intermediate for antiviral agents.

Request Bulk Pricing

Product Technical Details

Product Overview

1H-Pyrazole-1-carboxamidine Hydrochloride is a highly specialized organic compound widely recognized for its critical role in modern pharmaceutical manufacturing. As a refined chemical intermediate, this substance serves as an essential building block in the synthesis of complex therapeutic agents. Our facility produces this compound under strict quality control protocols to ensure consistency and reliability for research and industrial applications. The molecular structure features a pyrazole ring substituted with a carboxamidine group, stabilized in hydrochloride salt form to enhance handling and solubility during downstream processing.

We understand that precision is paramount in medicinal chemistry. Therefore, our production process focuses on maximizing purity while minimizing impurities that could affect subsequent reaction steps. This product is particularly valued in the development of antiviral medications, where structural integrity and chemical stability are non-negotiable requirements for regulatory compliance and efficacy.

Technical Specifications

ParameterValue
CAS Number4023-02-3
Molecular FormulaC4H7ClN4
Molecular Weight146.578 g/mol
AppearanceWhite to light yellow crystal
Assay (Purity)≥97.0%
Melting Point167-170 °C
Density2.2 g/cm3
Boiling Point891.5 °C at 760 mmHg
Flash Point493 °C
Refractive Index1.724

Industrial Applications

The primary application of 1H-Pyrazole-1-carboxamidine Hydrochloride lies in the pharmaceutical sector, specifically as a precursor in the synthesis of Zanamivir. Zanamivir is a well-known neuraminidase inhibitor used in the treatment of influenza, highlighting the importance of this intermediate in global health supply chains. Beyond this specific use, the compound is utilized in various organic synthesis routes where pyrazole derivatives are required for constructing heterocyclic frameworks.

Research laboratories and manufacturing plants rely on this material for developing new antiviral therapies and optimizing existing production pathways. Its high reactivity and stable salt form make it an ideal candidate for scale-up processes, ensuring that transition from laboratory bench to industrial reactor proceeds smoothly without unexpected deviations in yield or quality.

Quality Assurance and Storage

Quality is the cornerstone of our chemical supply service. Every batch of 1H-Pyrazole-1-carboxamidine Hydrochloride undergoes rigorous analytical testing, including HPLC and NMR spectroscopy, to verify identity and purity levels. We provide a comprehensive Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes.

  • Packaging is available in 25 kg drums, with customization options to meet specific logistical requirements.
  • Storage recommendations include keeping the material in a cool, ventilated area away from direct sunlight and moisture.
  • Our supply chain ensures stable availability for long-term projects and bulk procurement needs.
  • Technical support is available to assist with integration into your specific synthesis protocols.

By choosing our company as your partner, you gain access to a reliable source of high-performance chemical intermediates backed by decades of industry expertise. We are committed to supporting your innovation goals with products that meet the highest international standards for safety and quality.