Intermediates

1H-Pyrrolo[2,3-b]pyridin-5-ol

  • CAS No.98549-88-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 1H-Pyrrolo[2,3-b]pyridin-5-ol intermediate for pharmaceutical synthesis. Reliable supply with COA.

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Product Technical Details

Product Overview

Our company is pleased to offer premium grade 1H-Pyrrolo[2,3-b]pyridin-5-ol, a critical heterocyclic building block designed for advanced pharmaceutical research and development. This compound serves as a vital precursor in the synthesis of complex therapeutic agents, particularly within the oncology sector. As a leading global manufacturer, we understand the stringent requirements of modern drug discovery and provide materials that meet the highest standards of chemical integrity and consistency.

The molecular structure of this pyrrolopyridine derivative offers unique reactivity profiles, making it an indispensable tool for medicinal chemists working on kinase inhibitors and other targeted therapies. Our production facilities utilize state-of-the-art synthesis routes to ensure batch-to-batch reproducibility. We prioritize supply chain security to guarantee that your research and production timelines are never compromised by material shortages.

Technical Specifications

Quality control is the cornerstone of our manufacturing process. Every batch of 1H-Pyrrolo[2,3-b]pyridin-5-ol undergoes rigorous analytical testing using high-performance liquid chromatography and nuclear magnetic resonance spectroscopy. The following table outlines the key physical and chemical parameters that define our standard commercial grade product.

ParameterSpecification
Chemical Name1H-Pyrrolo[2,3-b]pyridin-5-ol
CAS Number98549-88-3
Molecular FormulaC8H8N2O
Molecular Weight148.16 g/mol
AppearanceWhite to off-white powder
Purity≥98.0%
Single Impurity≤0.15%
Water Content≤0.50%
Melting Point219-220°C

Industrial Applications

This chemical intermediate is primarily utilized in the multi-step synthesis of active pharmaceutical ingredients. It plays a crucial role in the construction of fused ring systems found in various novel therapeutics. Specifically, it is recognized as a key intermediate in the production pathway for certain BCL-2 inhibitors used in cancer treatment protocols. The high purity levels we maintain ensure that downstream reactions proceed with optimal yield and minimal byproduct formation.

Beyond oncology, this building block has potential applications in the development of anti-inflammatory agents and other small molecule drugs. Our technical team can provide guidance on optimal storage and handling conditions to maintain stability during your synthesis processes. We support both large-scale manufacturing needs and smaller research quantities to accommodate diverse project scopes.

Quality Assurance and Storage

We adhere to strict quality management systems to ensure product safety and efficacy. Each shipment is accompanied by a comprehensive Certificate of Analysis detailing the test results for that specific batch. Our packaging solutions are designed to protect the material from moisture and light degradation during transit. Standard packaging includes sealed cardboard drums suitable for international shipping.

For long-term storage, we recommend keeping the container tightly closed in a cool, dry, and well-ventilated area away from direct sunlight. Proper handling procedures should be followed in accordance with local safety regulations. Our commitment to excellence extends beyond the product itself, encompassing responsive customer service and flexible logistics options to meet your specific operational requirements globally.