Intermediates

(1R,2R)-(-)-1,2-Diaminocyclohexane

  • CAS No.20439-47-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity (1R,2R)-(-)-1,2-Diaminocyclohexane is a critical chiral intermediate used extensively in the synthesis of Oxaliplatin and other advanced pharmaceutical APIs.

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Product Technical Details

Product Overview

(1R,2R)-(-)-1,2-Diaminocyclohexane is a premium chiral building block essential for modern pharmaceutical synthesis. As a specialized intermediate, this compound plays a pivotal role in the production of high-value anticancer agents, specifically serving as a key precursor in the manufacturing process of Oxaliplatin. Our facility adheres to strict quality management systems to ensure every batch meets rigorous international standards for stereochemical purity and chemical stability.

We understand the critical nature of chiral intermediates in drug development. Therefore, our production lines are optimized to maintain high enantiomeric excess, ensuring downstream synthesis efficiency. This product is supplied exclusively to licensed pharmaceutical manufacturers and research institutions for legitimate industrial applications.

Key Specifications

Quality control is paramount in the supply of fine chemical intermediates. We employ advanced analytical techniques, including HPLC and GC-MS, to verify composition and purity levels. The following table outlines the standard technical specifications for our bulk supply:

ParameterSpecification
CAS Number20439-47-8
Molecular FormulaC6H14N2
Molecular Weight114.19 g/mol
AppearanceWhite Crystalline Powder
Purity (HPLC)≥98.0%
Moisture Content≤1.0%
Boiling Point86-88 °C at 23mmHg
Melting Point41-45 °C

Industrial Applications

The primary application of (1R,2R)-(-)-1,2-Diaminocyclohexane lies in the pharmaceutical sector, specifically within the realm of oncology drug synthesis. It acts as a chiral ligand or structural component in the formation of platinum-based coordination complexes. Beyond Oxaliplatin production, this diamine derivative is utilized in the development of various catalytic systems and asymmetric synthesis routes.

  • Essential intermediate for Oxaliplatin API manufacturing.
  • Used in asymmetric catalysis and ligand design.
  • Supports research into novel neurological therapeutics.
  • Compatible with large-scale industrial synthesis routes.

Storage and Handling

To maintain product integrity, proper storage conditions must be observed. The compound should be kept in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Containers must remain tightly closed to prevent moisture absorption, which could affect purity levels. We recommend using standard personal protective equipment during handling to ensure safety compliance in industrial settings.

Our logistics team ensures secure packaging using 25kg cardboard drums or customized solutions based on client requirements. Global shipping is available with full documentation, including Certificates of Analysis (COA) and safety data sheets. Partner with us for reliable supply chains and consistent quality in your pharmaceutical production processes.