Intermediates

(1R,2R)-1,2-Diphenylethane-1,2-diamine

  • CAS No.35132-20-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity chiral building block designed for asymmetric synthesis and catalytic applications. Ideal ligand for specialized organic reactions.

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Product Technical Details

Product Overview

(1R,2R)-1,2-Diphenylethane-1,2-diamine is a premier chiral diamine extensively utilized in the field of asymmetric synthesis. As a critical building block, this compound serves as a foundational element for constructing complex molecular architectures with high stereoselectivity. Our manufacturing process ensures exceptional enantiomeric purity, making it an indispensable reagent for pharmaceutical research and fine chemical production. The specific (1R,2R) configuration provides unique spatial properties that are essential for effective chiral catalysis.

Produced under strict quality control standards, this diamine exhibits consistent physical properties suitable for demanding laboratory and industrial environments. The compound is characterized by its stability and reactivity profile, which aligns perfectly with the requirements of modern organic synthesis protocols. Whether used in academic research or large-scale production, this material delivers reliable performance.

Technical Specifications

ParameterValue
Chemical Name(1R,2R)-1,2-Diphenylethane-1,2-diamine
CAS Number35132-20-8
Molecular FormulaC14H16N2
Molecular Weight212.29 g/mol
Purity≥98%
AppearanceOff-white powder
Melting Point81-84°C
Boiling Point353.9°C at 760 mmHg
Density1.106 g/cm3
Storage2-8°C

Industrial Applications

This chiral diamine is predominantly employed as a ligand in transition metal-catalyzed asymmetric reactions. It plays a pivotal role in Noyori asymmetric hydrogenation, enabling the efficient production of enantiomerically enriched alcohols and amines. The robustness of the ligand system derived from this diamine allows for high turnover numbers and excellent enantioselectivity across various substrate classes.

  • Asymmetric hydrogenation catalysts
  • Chiral auxiliary synthesis
  • Pharmaceutical intermediate production
  • Fine chemical manufacturing
  • Research and development of new chiral methodologies

Beyond catalysis, it serves as a versatile intermediate for the synthesis of complex heterocyclic compounds. Its utility extends into the development of novel therapeutic agents where stereochemistry dictates biological activity. Manufacturers rely on this material to maintain consistency in multi-step synthesis routes, ensuring final product quality.

Quality Assurance and Storage

Every batch undergoes rigorous analytical testing to verify chemical identity and purity levels. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing spectral data and purity assessments. Proper storage is crucial to maintain the integrity of the product. It is recommended to keep the material in a cool, dry place within the specified temperature range of 2-8°C. Protect from moisture and light to prevent degradation over extended periods.

Our global supply chain ensures timely delivery while maintaining cold chain logistics where necessary. As a trusted manufacturer, we commit to providing technical support and documentation to facilitate your regulatory compliance and production efficiency. Contact our sales team for bulk pricing and custom packaging options tailored to your specific operational needs.