(1S)-(+)-10-Camphorsulfonic Acid
- CAS No.3144-16-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (1S)-(+)-10-Camphorsulfonic Acid (CAS 3144-16-9) serves as a critical chiral resolving agent and pharmaceutical intermediate for global synthesis applications.
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Product Overview
(1S)-(+)-10-Camphorsulfonic Acid, frequently abbreviated as CSA, stands as a premier chiral sulfonic acid extensively utilized in advanced organic synthesis and pharmaceutical manufacturing. Derived from natural camphor sources, this compound functions as an essential resolving agent designed for separating racemic mixtures into distinct enantiomers. Our facility specializes in producing high-purity grades suitable for demanding chemical processes where stereochemical integrity is paramount for product efficacy.
As a leading global manufacturer, we ensure consistent quality through rigorous analytical testing and state-of-the-art production protocols. The product is characterized by its exceptional optical purity and thermal stability, making it a preferred choice for synthesizing complex active pharmaceutical ingredients. Whether utilized in laboratory-scale research or industrial-scale production, our camphorsulfonic acid meets international standards for purity and performance.
Chemical Properties and Significance
The chemical structure of (1S)-(+)-10-Camphorsulfonic Acid features a robust bicyclic framework with a sulfonic acid group, providing strong acidity and excellent solubility in various organic solvents. This unique configuration allows it to form diastereomeric salts with chiral bases, facilitating efficient separation processes. The high specific rotation value indicates superior enantiomeric excess, which is critical for downstream applications in fine chemistry.
Quality control remains the cornerstone of our manufacturing process. Each batch undergoes comprehensive testing to verify physical and chemical properties against strict internal standards. We employ advanced chromatography and spectroscopy methods to ensure that every shipment delivers the expected performance. This commitment to excellence minimizes variability in your synthesis routes and enhances overall yield.
Key Specifications
The following table outlines the standard specifications for our premium grade material, demonstrating our capability to supply consistent high-quality chemicals:
| Items of Analysis | Standard of Analysis | Test Results |
|---|---|---|
| Appearance | White to off-white crystalline powder | Conform |
| Loss on drying | ≤1.0% | 0.35% |
| Specific Rotation | +21° ~ +23° | +21.5° |
| Melting point | 192℃-202℃ | 197.4-198.3℃ |
| Purity | ≥99% | 99.78% |
| Conclusion | Conforms to Factory Standard | |
Industrial Applications
This chiral acid is indispensable in the production of various pharmaceutical intermediates and fine chemicals. It is frequently employed in the synthesis of cardiovascular therapeutics, including intermediates for clopidogrel sulfate and related compounds. Beyond pharmaceuticals, it finds significant application in asymmetric catalysis and the preparation of optically active materials.
- Chiral resolution of racemic amines and alcohols.
- Catalyst in asymmetric organic synthesis reactions.
- Intermediate for cardiovascular pharmaceutical APIs.
- Research and development in stereochemistry.
Storage and Handling
To maintain optimal quality, store this product in a sealed container within a cool and dry environment, ideally between 2-8°C. Protect the material from moisture and strong light or heat sources to prevent degradation. Proper handling ensures the longevity and efficacy of the chemical for your specific applications. We offer flexible packing options, including 25kg cardboard drums, tailored to customer requirements and logistics needs.
