2,3-Difluoroanisole
- CAS No.134364-69-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2,3-Difluoroanisole intermediate for pharmaceutical and liquid crystal synthesis. Available in bulk with strict quality control.
Request Bulk PricingProduct Technical Details
Product Overview
2,3-Difluoroanisole is a specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern featuring two fluorine atoms adjacent to a methoxy group on the benzene ring, this chemical offers distinct reactivity profiles essential for complex molecule construction. Our facility produces this intermediate under stringent quality management systems to ensure consistent performance in downstream applications.
The introduction of fluorine atoms into organic molecules is a cornerstone strategy in medicinal chemistry and material science. This specific isomer provides excellent metabolic stability and lipophilicity modulation when incorporated into larger pharmaceutical structures. Furthermore, its physical properties, including a defined boiling point and refractive index, make it suitable for precise industrial processes requiring high reliability.
Key Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 134364-69-5 |
| Molecular Formula | C7H6F2O |
| Molecular Weight | 144.12 g/mol |
| Appearance | Colorless transparent liquid |
| Assay (Purity) | ≥99.0% |
| Moisture Content | ≤0.2% |
| Density | 1.24 g/cm3 |
| Boiling Point | 144.5°C |
| Refractive Index | 1.452 |
Industrial Applications
This fluorinated intermediate is primarily utilized in the synthesis of advanced pharmaceutical active ingredients. The electron-withdrawing nature of the fluorine substituents influences the electronic density of the aromatic ring, facilitating specific nucleophilic substitution reactions required for drug development pipelines. It is particularly valued in the creation of kinase inhibitors and other targeted therapeutics where metabolic stability is paramount.
Beyond the pharmaceutical sector, 2,3-Difluoroanisole finds significant application in the agrochemical industry for developing next-generation pesticides with improved environmental profiles. Additionally, it serves as a precursor in the manufacture of liquid crystal materials, where precise molecular geometry and purity are critical for display performance. Our manufacturing process ensures the removal of isomeric impurities that could detrimentally affect liquid crystal alignment.
Quality Assurance and Storage
We maintain a robust quality control protocol for every batch produced. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) verifying purity, moisture content, and physical constants. Our analytical laboratories utilize gas chromatography and high-performance liquid chromatography to guarantee the ≥99.0% assay specification.
- Packaged in 200 kg drums or customized containers based on client logistics requirements.
- Storage recommendations include keeping the material in a cool, ventilated area away from direct sunlight.
- Safety data sheets (MSDS) are provided to ensure safe handling regarding flash point and chemical stability.
- Global shipping capabilities ensure timely delivery to manufacturing sites worldwide.
Partner with us for a reliable supply chain of high-performance chemical intermediates. Our commitment to quality and regulatory compliance makes us a preferred vendor for R&D departments and large-scale production facilities alike.
