2,3-Difluorophenol
- CAS No.6418-38-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2,3-Difluorophenol (CAS 6418-38-8) is a premium fluorinated building block designed for pharmaceutical intermediate synthesis and advanced organic chemistry applications.
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Product Overview
2,3-Difluorophenol is a highly specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis and medicinal chemistry. As a key intermediate, this compound is extensively utilized in the development of pharmaceutical agents, agrochemicals, and advanced functional materials. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for research and industrial scale production where consistency and quality are paramount.
The introduction of fluorine atoms into organic molecules often significantly enhances metabolic stability, lipophilicity, and bioavailability of the final drug product. Consequently, 2,3-Difluorophenol is frequently employed in the synthesis of complex molecular structures requiring precise substitution patterns on the aromatic ring. We adhere to strict quality control protocols to guarantee that every batch meets rigorous international standards.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2,3-Difluorophenol |
| CAS Number | 6418-38-8 |
| Molecular Formula | C6H4F2O |
| Molecular Weight | 130.09 g/mol |
| Appearance | White crystals |
| Purity | ≥99.0% |
| Melting Point | 39-42 °C |
| Boiling Point | 54 °C at 25 mm Hg |
| Density | 1.351 g/cm3 |
| Refractive Index | 1.495 |
Industrial Applications
This fluorinated phenol derivative is primarily utilized as a versatile intermediate in the pharmaceutical industry. It serves as a precursor for various therapeutic compounds where the difluoro substitution pattern is required to modulate electronic properties and steric hindrance. Common applications include the synthesis of kinase inhibitors, receptor modulators, and other small molecule drugs.
Beyond pharmaceuticals, 2,3-Difluorophenol finds utility in the agrochemical sector for developing novel pesticides and herbicides. Its chemical stability and reactivity profile make it suitable for diverse synthetic transformations, including nucleophilic aromatic substitution and cross-coupling reactions. Researchers value this compound for its reliability in multi-step synthesis routes.
Quality Assurance and Safety
We maintain a robust quality management system to ensure product integrity. Each shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. Our facility operates under strict safety guidelines to handle fluorinated compounds responsibly. Proper handling procedures should always be followed to minimize exposure risks.
- Consistent high purity suitable for sensitive reactions
- Comprehensive documentation and regulatory support
- Stable supply chain for global distribution
- Technical support available for synthesis optimization
Storage and Handling
To maintain optimal quality, 2,3-Difluorophenol should be stored in a tightly closed container within a cool, dry, and well-ventilated area. It is essential to keep the material away from incompatible substances such as strong oxidizing agents and bases. Personnel handling this chemical should wear appropriate personal protective equipment, including gloves and safety goggles, to prevent skin and eye contact. In case of spillage, standard chemical containment procedures should be implemented immediately.
