Intermediates

2,5-Difluorobenzaldehyde

  • CAS No.2646-90-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2,5-Difluorobenzaldehyde (CAS 2646-90-4) is a vital fluorinated building block for pharmaceutical and liquid crystal synthesis.

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Product Technical Details

Product Overview

2,5-Difluorobenzaldehyde is a specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern, this chemical intermediate offers exceptional reactivity for nucleophilic substitutions and condensation reactions. Our manufacturing process ensures high consistency and purity, making it an ideal choice for complex molecular constructions in the pharmaceutical and agrochemical sectors.

As a key precursor, this difluoro-substituted benzaldehyde derivative facilitates the introduction of fluorine atoms into target molecules, enhancing metabolic stability and bioavailability in drug candidates. The compound is supplied as a clear liquid, ready for immediate integration into various synthetic routes without extensive purification requirements.

Technical Specifications

Parameter Specification
CAS Number 2646-90-4
Molecular Formula C7H4F2O
Molecular Weight 142.11 g/mol
Appearance Colorless to light yellow clear liquid
Purity (GC) ≥98.0%
Density 1.308 g/mL at 25 °C
Boiling Point 67-69 °C at 17 mm Hg
Refractive Index n20/D 1.498

Industrial Applications

This fluorinated intermediate finds extensive utility across multiple high-value industries. In pharmaceutical manufacturing, it is employed in the synthesis of kinase inhibitors and other therapeutic agents where fluorine substitution is crucial for optimizing pharmacokinetic properties. The compound's stability under various reaction conditions allows for versatile usage in multi-step synthesis protocols.

Beyond medicine, 2,5-Difluorobenzaldehyde is utilized in the production of advanced liquid crystal materials, contributing to the performance of display technologies. It also serves as a vital component in agrochemical formulations, aiding in the development of novel pesticides with improved environmental profiles. Our global supply chain ensures timely delivery for large-scale industrial projects.

Quality Assurance and Safety

Quality is paramount in our production facility. Each batch undergoes rigorous analytical testing, including gas chromatography and spectral analysis, to confirm identity and purity levels. We provide comprehensive Certificates of Analysis (COA) with every shipment to ensure compliance with international standards. Proper handling procedures should be followed, including the use of personal protective equipment and adequate ventilation, as per standard safety guidelines for fluorinated organic compounds.