2,6-Dichloropurine
- CAS No.5451-40-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2,6-Dichloropurine intermediate designed for pharmaceutical synthesis, specifically for Clofarabine production with reliable quality assurance.
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Product Overview
2,6-Dichloropurine is a highly specialized heterocyclic compound that serves as a critical building block in the field of medicinal chemistry. As a chlorinated purine derivative, this molecule possesses unique reactivity profiles that make it indispensable for the synthesis of complex nucleoside analogs. Our facility produces this compound under strict quality control standards to ensure consistency across batches, catering to the rigorous demands of pharmaceutical research and development teams worldwide.
The chemical structure features chlorine substituents at the 2 and 6 positions of the purine ring, which facilitates selective nucleophilic substitution reactions. This characteristic is particularly valuable when constructing modified nucleosides intended for therapeutic applications. We understand the importance of reliability in the supply chain for active pharmaceutical ingredient precursors, and our manufacturing processes are optimized to deliver material that meets exacting specifications.
Technical Specifications
We maintain a robust quality assurance framework to verify the identity and purity of every batch produced. The following table outlines the key physical and chemical parameters associated with our standard grade material. Custom specifications may be available upon request for specific project requirements.
| Parameter | Specification |
|---|---|
| CAS Number | 5451-40-1 |
| Molecular Formula | C5H2Cl2N4 |
| Molecular Weight | 189.00 g/mol |
| Appearance | Off-white powder |
| Assay (HPLC) | ≥99.0% |
| Melting Point | 185-195°C |
| Density | 1.792 g/cm3 |
Industrial Applications
The primary application of 2,6-Dichloropurine lies in the synthesis of anticancer agents, most notably as a key intermediate in the production of Clofarabine. This compound acts as a foundational scaffold upon which further functionalization can occur to create biologically active molecules. Beyond oncology, purine derivatives are increasingly explored in antiviral and immunomodulatory research, expanding the potential utility of this chemical building block.
Chemists utilize this material for various organic synthesis routes where high purity is paramount to prevent side reactions during downstream processing. Our product supports both laboratory-scale discovery and pilot-scale production, ensuring a seamless transition from research to commercial manufacturing. The versatility of the chloro groups allows for diverse coupling strategies, making it a preferred choice for process chemists.
Quality Assurance and Packaging
Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing the test results against our internal standards. We employ advanced analytical techniques, including High-Performance Liquid Chromatography (HPLC), to verify assay levels and impurity profiles. Our packaging options are designed to maintain product integrity during transit and storage.
- Standard packing includes 25 kg drums lined with moisture-proof bags.
- Custom packaging solutions are available based on customer requirements.
- Storage recommendations include keeping the material in a cool, ventilated area away from direct sunlight.
- Strict adherence to safety data sheet guidelines ensures safe handling throughout the supply chain.
As a global manufacturer, we are committed to providing not just chemicals, but complete technical support. Our team is ready to assist with documentation, regulatory inquiries, and logistics to ensure your project timelines are met without compromise.
