Intermediates

2-(1H-Imidazol-1-yl)acetic Acid Hydrochloride

  • CAS No.87266-37-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-(1H-Imidazol-1-yl)acetic Acid Hydrochloride (CAS 87266-37-3) designed for pharmaceutical synthesis. Ideal intermediate for Zoledronic acid production with ≥98% assay.

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Product Technical Details

Product Overview

2-(1H-Imidazol-1-yl)acetic Acid Hydrochloride is a specialized organic compound characterized by its distinct imidazole ring structure coupled with an acetic acid moiety. This chemical serves as a critical building block in the synthesis of complex pharmaceutical agents, particularly within the bisphosphonate class. Our manufacturing process ensures exceptional stability and reactivity, making it a preferred choice for research and development teams focused on advanced organic synthesis.

As a hydrochloride salt, this compound offers improved solubility profiles compared to its free acid form, facilitating smoother reaction kinetics in various solvent systems. The molecular architecture allows for versatile functionalization, enabling chemists to construct intricate molecular frameworks required for modern therapeutic applications. We prioritize consistency in every batch to support scalable production environments.

Technical Specifications

ParameterValue
Chemical Name2-(1H-Imidazol-1-yl)acetic Acid Hydrochloride
CAS Number87266-37-3
Molecular FormulaC5H7ClN2O2
Molecular Weight162.57 g/mol
Purity≥98%
AppearanceWhite Powder
Melting Point193-195ºC
Moisture Content≤0.5%

Industrial Applications

The primary application of this intermediate lies in the pharmaceutical sector, specifically serving as a key precursor in the manufacturing of Zoledronic Acid. Zoledronic Acid is a potent bisphosphonate used clinically to treat bone resorption disorders, highlighting the importance of high-quality starting materials. Beyond this specific pathway, the compound is utilized in broader medicinal chemistry campaigns where imidazole derivatives are required for structure-activity relationship studies.

  • Essential intermediate for Zoledronic Acid synthesis.
  • Utilized in pharmaceutical R&D for novel drug discovery.
  • Supports large-scale industrial manufacturing processes.
  • Compatible with various organic synthesis routes.

Quality Assurance And Storage

Quality control is paramount in our production facility. Each batch undergoes rigorous analytical testing, including HPLC and NMR spectroscopy, to verify identity and purity levels. We provide a comprehensive Certificate of Analysis (COA) with every shipment to ensure transparency and compliance with international standards. Our commitment to industrial purity guarantees minimal impurity profiles, reducing downstream purification burdens for our clients.

For optimal stability, the product should be stored in a cool and dry environment within well-closed containers. It is essential to protect the material from moisture and strong light or heat sources to prevent degradation. We offer flexible packaging options, typically supplying in 25kg cardboard drums, but can accommodate custom requirements based on specific logistical needs. Our global distribution network ensures timely delivery while maintaining product integrity throughout the supply chain.